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Chemical Compound Review

Trenimon     2,3,5-tris(aziridin-1- yl)cyclohexa-2,5...

Synonyms: Prenimon, Treninon, Oncoredox, Oncovedex, Trenimone, ...
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Disease relevance of TRIAZIQUONE


High impact information on TRIAZIQUONE


Chemical compound and disease context of TRIAZIQUONE


Biological context of TRIAZIQUONE


Anatomical context of TRIAZIQUONE


Associations of TRIAZIQUONE with other chemical compounds


Gene context of TRIAZIQUONE


Analytical, diagnostic and therapeutic context of TRIAZIQUONE


  1. Modulation of trenimon-induced cytotoxicity by DT-diaphorase in isolated rat hepatocytes under aerobic versus hypoxic conditions. Silva, J.M., Rao, D.N., O'Brien, P.J. Cancer Res. (1992) [Pubmed]
  2. Interaction of the alkylating antitumor agent 2,3,5-tris(ethyleneimino)benzoquinone with the plasma membrane of Ehrlich ascites tumor cells. Ihlenfeldt, M., Gantner, G., Harrer, M., Puschendorf, B., Putzer, H., Grunicke, H. Cancer Res. (1981) [Pubmed]
  3. Position of chromosomes in the human interphase nucleus. An analysis of nonhomologous chromatid translocations in lymphocyte cultures after Trenimon treatment and from patients with Fanconi's anemia and Bloom's syndrome. Hager, H.D., Schroeder-Kurth, T.M., Vogel, F. Hum. Genet. (1982) [Pubmed]
  4. Elimination of spontaneous and chemically induced chromosome aberrations in mice during early embryogenesis. Basler, A., Buselmaier, B., Röhrborn, G. Hum. Genet. (1976) [Pubmed]
  5. Different sensitivity of diploid and trisomic cells from patients with Down syndrome mosaic after treatment with the trifunctional alkylating agent trenimon. Aldenhoff, P., Wegner, R.D., Sperling, K. Hum. Genet. (1980) [Pubmed]
  6. Effects of conjugated and nonconjugated antithymocyte globulin and trenimon on T lymphocytes and skin graft rejection. Beatty, J.D., Friesen, E., Linford, J.H., Israels, L.G. Transplantation (1978) [Pubmed]
  7. Induced dominant lethal mutations and cytotoxic effects in germ cells of Drosophila melanogaster with Trenimon, PDMT and sodium monofluorophosphate. Büchi, R. Genetics (1977) [Pubmed]
  8. Fanconi anemia complementation group E: clinical and cytogenetic data of the first patient. Wegner, R.D., Henrichs, I., Joenje, H., Schroeder-Kurth, T. Clin. Genet. (1996) [Pubmed]
  9. Sister chromatid exchanges in human leukocyte chromosomes: spontaneous and induced frequencies in early- and late-proliferating cells in vitro. Beek, B., Obe, G. Hum. Genet. (1979) [Pubmed]
  10. Chromosome behaviour during early meiotic prophase of mouse primary spermatocytes. Oud, J.L., Reutlinger, A.H. Chromosoma (1981) [Pubmed]
  11. The anticlastogenic effect of various combinations of cysteamine, AET, HCT, and amino acids on chromosome damage by trenimon and bleomycin in human lymphocytes in vitro. Gebhart, E. Hum. Genet. (1978) [Pubmed]
  12. Evaluation of the co-mutagenicity of ethanol and delta 9-tetrahydrocannabinol with Trenimon. Berryman, S.H., Anderson, R.A., Weis, J., Bartke, A. Mutat. Res. (1992) [Pubmed]
  13. Effects of caffeine on sister chromatid exchange (SCE) after exposure to UV light or triaziquone studied with a fluorescence plus giemsa (FPG) technique. Vogel, W., Bauknecht, T. Hum. Genet. (1978) [Pubmed]
  14. Influence of Neurospora endonuclease on trenimon-induced structural chromosomal aberrations and sister-chromatid exchanges in human peripheral lymphocytes and Chinese hamster ovary cells. Nowak, C., Obe, G. Mutat. Res. (1985) [Pubmed]
  15. The effect of sodium fluoride on DNA synthesis, mitotic indices and chromosomal aberrations in human leukocytes treated with trenimon in vitro. Slacik-Erbn, R., Obe, G. Mutat. Res. (1976) [Pubmed]
  16. Effects of 50-hertz electromagnetic fields on proliferation and on chromosomal alterations in human peripheral lymphocytes untreated or pretreated with chemical mutagens. Rosenthal, M., Obe, G. Mutat. Res. (1989) [Pubmed]
  17. Isolation and characterization of additional genes influencing resistance to various mutagens in the yeast Saccharomyces cerevisiae. Haase, E., Servos, J., Brendel, M. Curr. Genet. (1992) [Pubmed]
  18. The lack of effects of alkylating agents on mammalian cell membranes. Ankel, E.G., Ring, B.J., Lai, C.S., Holcenberg, J.S. International journal of tissue reactions. (1986) [Pubmed]
  19. Spermatogenic delay and increased chiasma frequency in T70H/+ male mice with hydroxyurea-Trenimon limited spermatocyte populations. Wauben-Penris, P.J., van Meel, G.P., de Boer, P. Can. J. Genet. Cytol. (1985) [Pubmed]
  20. Is there a general relationship between estimated chromosome distances in interphase and location of genes with related functions? Vogel, F., Krüger, J. Hum. Genet. (1983) [Pubmed]
  21. Molecular mechanisms of trenimon-induced cytotoxicity in resistant L5178Y/HBM10 cells. Silva, J.M., O'Brien, P.J. Int. J. Radiat. Oncol. Biol. Phys. (1992) [Pubmed]
  22. Detection of induced resistance in short-term-tests. Adriamycin-resistant sarcoma 180. Volm, M., Lindner, C. Zeitschrift für Krebsforschung und klinische Onkologie. Cancer research and clinical oncology. (1978) [Pubmed]
  23. The effect of in situ isolated perfusion of experimental renal tumors with cytotoxic agents in high concentration. Asbach, H.W., Bersch, W. Urologia internationalis. (1980) [Pubmed]
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