Gene Review:
Syt1 - synaptotagmin I
Mus musculus
Synonyms:
AW124717, G630098F17Rik, Synaptotagmin I, Synaptotagmin-1, SytI, ...
- Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice. Neurath, M.F., Pettersson, S., Meyer zum Büschenfelde, K.H., Strober, W. Nat. Med. (1996)
- Infrequent normal B lymphocytes express features of B-chronic lymphocytic leukemia. Caligaris-Cappio, F., Gobbi, M., Bofill, M., Janossy, G. J. Exp. Med. (1982)
- A murine model of chronic inflammation-induced intestinal fibrosis down-regulated by antisense NF-kappa B. Lawrance, I.C., Wu, F., Leite, A.Z., Willis, J., West, G.A., Fiocchi, C., Chakravarti, S. Gastroenterology (2003)
- The synaptic vesicle protein synaptotagmin associates with calcium channels and is a putative Lambert-Eaton myasthenic syndrome antigen. Leveque, C., Hoshino, T., David, P., Shoji-Kasai, Y., Leys, K., Omori, A., Lang, B., el Far, O., Sato, K., Martin-Moutot, N. Proc. Natl. Acad. Sci. U.S.A. (1992)
- Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor. Ray, A., Prefontaine, K.E. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Deficits in memory and motor performance in synaptotagmin IV mutant mice. Ferguson, G.D., Anagnostaras, S.G., Silva, A.J., Herschman, H.R. Proc. Natl. Acad. Sci. U.S.A. (2000)
- The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors. Okada, Y., Yamazaki, H., Sekine-Aizawa, Y., Hirokawa, N. Cell (1995)
- Synaptotagmin I functions as a calcium regulator of release probability. Fernández-Chacón, R., Königstorfer, A., Gerber, S.H., García, J., Matos, M.F., Stevens, C.F., Brose, N., Rizo, J., Rosenmund, C., Südhof, T.C. Nature (2001)
- Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA. Chen, F.E., Huang, D.B., Chen, Y.Q., Ghosh, G. Nature (1998)
- A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation. Sanjabi, S., Williams, K.J., Saccani, S., Zhou, L., Hoffmann, A., Ghosh, G., Gerondakis, S., Natoli, G., Smale, S.T. Genes Dev. (2005)
- The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms. Scott, M.L., Fujita, T., Liou, H.C., Nolan, G.P., Baltimore, D. Genes Dev. (1993)
- Molecular basis of complement resistance of human melanoma cells expressing the C3-cleaving membrane protease p65. Ollert, M.W., Kadlec, J.V., Petrella, E.C., Bredehorst, R., Vogel, C.W. Cancer Res. (1993)
- Antisense oligonucleotides to NF-kappaB improve survival in bleomycin-induced pneumopathy of the mouse. Zhang, X.Y., Shimura, S., Masuda, T., Saitoh, H., Shirato, K. Am. J. Respir. Crit. Care Med. (2000)
- Therapeutic effect of intracolonically administered nuclear factor kappa B (p65) antisense oligonucleotide on mouse dextran sulphate sodium (DSS)-induced colitis. Murano, M., Maemura, K., Hirata, I., Toshina, K., Nishikawa, T., Hamamoto, N., Sasaki, S., Saitoh, O., Katsu, K. Clin. Exp. Immunol. (2000)
- Effect of antisense oligonucleotides to nuclear factor-kappaB on the survival of LPS-induced ARDS in mouse. Saitoh, H., Masuda, T., Zhang, X.Y., Shimura, S., Shirato, K. Exp. Lung Res. (2002)
- Identification of the polymerase polyprotein products p72 and p65 of the murine coronavirus MHV-JHM. Gao, H.Q., Schiller, J.J., Baker, S.C. Virus Res. (1996)
- Different effects on fast exocytosis induced by synaptotagmin 1 and 2 isoforms and abundance but not by phosphorylation. Nagy, G., Kim, J.H., Pang, Z.P., Matti, U., Rettig, J., Südhof, T.C., Sørensen, J.B. J. Neurosci. (2006)
- Genomic structures of synaptotagmin II protein: comparison of exon-intron organization of the synaptotagmin gene family. Fukuda, M., Mikoshiba, K. Biochem. Biophys. Res. Commun. (2000)
- Synaptotagmin VI and VIII and syntaxin 2 are essential for the mouse sperm acrosome reaction. Hutt, D.M., Baltz, J.M., Ngsee, J.K. J. Biol. Chem. (2005)
- Genetic analysis of synaptotagmin 2 in spontaneous and Ca2+-triggered neurotransmitter release. Pang, Z.P., Sun, J., Rizo, J., Maximov, A., Südhof, T.C. EMBO J. (2006)
- The extravesicular domain of synaptotagmin-1 is released with the latent fibroblast growth factor-1 homodimer in response to heat shock. Tarantini, F., LaVallee, T., Jackson, A., Gamble, S., Mouta Carreira, C., Garfinkel, S., Burgess, W.H., Maciag, T. J. Biol. Chem. (1998)
- Synaptic vesicle and synaptic membrane glycoproteins during pre- and postnatal development of mouse cerebral cortex, cerebellum and spinal cord. Mayanil, C.S., Knepper, P.A. Dev. Neurosci. (1993)
- Inositol-1,3,4,5-tetrakisphosphate binding to C2B domain of IP4BP/synaptotagmin II. Fukuda, M., Aruga, J., Niinobe, M., Aimoto, S., Mikoshiba, K. J. Biol. Chem. (1994)
- Autonomous function of synaptotagmin 1 in triggering synchronous release independent of asynchronous release. Maximov, A., Südhof, T.C. Neuron (2005)
- Sr2+ binding to the Ca2+ binding site of the synaptotagmin 1 C2B domain triggers fast exocytosis without stimulating SNARE interactions. Shin, O.H., Rhee, J.S., Tang, J., Sugita, S., Rosenmund, C., Südhof, T.C. Neuron (2003)
- Distribution of the presynaptic calcium sensors, synaptotagmin I/II and synaptotagmin III, in the goldfish and rodent retinas. Berntson, A.K., Morgans, C.W. Journal of vision [electronic resource]. (2003)
- SNAP-25 and synaptotagmin 1 function in Ca2+-dependent reversible docking of granules to the plasma membrane. Chieregatti, E., Witkin, J.W., Baldini, G. Traffic (2002)
- The role of Snapin in neurosecretion: snapin knock-out mice exhibit impaired calcium-dependent exocytosis of large dense-core vesicles in chromaffin cells. Tian, J.H., Wu, Z.X., Unzicker, M., Lu, L., Cai, Q., Li, C., Schirra, C., Matti, U., Stevens, D., Deng, C., Rettig, J., Sheng, Z.H. J. Neurosci. (2005)
- Central pore residues mediate the p97/VCP activity required for ERAD. DeLaBarre, B., Christianson, J.C., Kopito, R.R., Brunger, A.T. Mol. Cell (2006)
- Kinetic efficiency of endocytosis at mammalian CNS synapses requires synaptotagmin I. Nicholson-Tomishima, K., Ryan, T.A. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Comparison of immunolocalization patterns for the synaptic vesicle proteins p65 and synapsin I in macaque monkey retina. Koontz, M.A., Hendrickson, A.E. Synapse (1993)
- Failure of lymphopoiesis after adoptive transfer of NF-kappaB-deficient fetal liver cells. Horwitz, B.H., Scott, M.L., Cherry, S.R., Bronson, R.T., Baltimore, D. Immunity (1997)
- Activation of the transcription factor NF-kappaB in Schwann cells is required for peripheral myelin formation. Nickols, J.C., Valentine, W., Kanwal, S., Carter, B.D. Nat. Neurosci. (2003)
- Organ-specific roles for transcription factor NF-kappaB in reovirus-induced apoptosis and disease. O'Donnell, S.M., Hansberger, M.W., Connolly, J.L., Chappell, J.D., Watson, M.J., Pierce, J.M., Wetzel, J.D., Han, W., Barton, E.S., Forrest, J.C., Valyi-Nagy, T., Yull, F.E., Blackwell, T.S., Rottman, J.N., Sherry, B., Dermody, T.S. J. Clin. Invest. (2005)