Gene Review:
Gne - glucosamine (UDP-N-acetyl)-2-epimerase/N...
Mus musculus
Synonyms:
2310066H07Rik, Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, DMRV, GLCNE, Glcne, ...
- A Gne knockout mouse expressing human V572L mutation develops features similar to distal myopathy with rimmed vacuoles or hereditary inclusion body myopathy. Malicdan, M.C., Noguchi, S., Nonaka, I., Hayashi, Y.K., Nishino, I. Hum. Mol. Genet. (2007)
- A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry. Shukla, D., Liu, J., Blaiklock, P., Shworak, N.W., Bai, X., Esko, J.D., Cohen, G.H., Eisenberg, R.J., Rosenberg, R.D., Spear, P.G. Cell (1999)
- Effects of D-glucosamine and 6-azauridine on nucleotide contents, 5-fluorouridine uptake, and cytotoxicity in TA3 mammary tumor cells. Holstege, A., Keppler, D. J. Natl. Cancer Inst. (1986)
- Delayed catabolism of apoB-48 lipoproteins due to decreased heparan sulfate proteoglycan production in diabetic mice. Ebara, T., Conde, K., Kako, Y., Liu, Y., Xu, Y., Ramakrishnan, R., Goldberg, I.J., Shachter, N.S. J. Clin. Invest. (2000)
- Molecular requirements for B-lymphocyte activation by Escherichia coli lipopolysaccharide. Raetz, C.R., Purcell, S., Takayama, K. Proc. Natl. Acad. Sci. U.S.A. (1983)
- Glycoprotein synthesis and inhibition of glycosylation by tunicamycin in preimplantation mouse embryos: compaction and trophoblast adhesion. Surani, M.A. Cell (1979)
- Insulin-stimulated hydrolysis of a novel glycolipid generates modulators of cAMP phosphodiesterase. Saltiel, A.R., Fox, J.A., Sherline, P., Cuatrecasas, P. Science (1986)
- Inflammatory toxin from Mycoplasma bovis: isolation and characterization. Geary, S.J., Tourtellotte, M.E., Cameron, J.A. Science (1981)
- Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responses. Wang, L., Fuster, M., Sriramarao, P., Esko, J.D. Nat. Immunol. (2005)
- Lipooligosaccharides (LOS) of Neisseria gonorrhoeae and Neisseria meningitidis have components that are immunochemically similar to precursors of human blood group antigens. Carbohydrate sequence specificity of the mouse monoclonal antibodies that recognize crossreacting antigens on LOS and human erythrocytes. Mandrell, R.E., Griffiss, J.M., Macher, B.A. J. Exp. Med. (1988)
- Loss of melanogenic properties in tyrosinases induced by glucosylation inhibitors within malignant melanoma cells. Imokawa, G., Mishima, Y. Cancer Res. (1982)
- Identification of a lipid A binding site in the acute phase reactant lipopolysaccharide binding protein. Tobias, P.S., Soldau, K., Ulevitch, R.J. J. Biol. Chem. (1989)
- The 170-kDa glucose-regulated stress protein is an endoplasmic reticulum protein that binds immunoglobulin. Lin, H.Y., Masso-Welch, P., Di, Y.P., Cai, J.W., Shen, J.W., Subjeck, J.R. Mol. Biol. Cell (1993)
- Deglycosylation of mucin from LS174T colon cancer cells by hydrogen fluoride treatment. Byrd, J.C., Lamport, D.T., Siddiqui, B., Kuan, S.F., Erickson, R., Itzkowitz, S.H., Kim, Y.S. Biochem. J. (1989)
- Chemical structure of lipid A from Porphyromonas (Bacteroides) gingivalis lipopolysaccharide. Ogawa, T. FEBS Lett. (1993)
- 2-Deoxyglucose selectively inhibits Fc and complement receptor-mediated phagocytosis in mouse peritoneal macrophages. I. Description of the inhibitory effect. Michl, J., Ohlbaum, D.J., Silverstein, S.C. J. Exp. Med. (1976)
- Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins. Wang, L., Brown, J.R., Varki, A., Esko, J.D. J. Clin. Invest. (2002)
- Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes. Vosseller, K., Wells, L., Lane, M.D., Hart, G.W. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Synthesis and glycosylation of the common alpha subunit of human glycoprotein hormones in mouse cells. Ramabhadran, T.V., Reitz, B.A., Tiemeier, D.C. Proc. Natl. Acad. Sci. U.S.A. (1984)
- Characterization of the multidrug resistance protein expressed in cell clones stably transfected with the mouse mdr1 cDNA. Schurr, E., Raymond, M., Bell, J.C., Gros, P. Cancer Res. (1989)
- Size variation of the M protein in group A streptococci. Fischetti, V.A., Jones, K.F., Scott, J.R. J. Exp. Med. (1985)
- Alterations in surface glycoproteins and level of sialyltransferase of cells transformed by a temperature-sensitive mutant of simian virus 40. Onodera, K., Yamaguchi, N., Kuchino, T., Aoi, Y. Proc. Natl. Acad. Sci. U.S.A. (1976)
- Receptor-mediated endocytosis of carcinoembryonic antigen by rat liver Kupffer cells. Toth, C.A., Thomas, P., Broitman, S.A., Zamcheck, N. Cancer Res. (1985)
- Energy metabolism and T-cell-mediated cytolysis. II. Selective inhibition of cytolysis by 2-deoxy-D-glucose. MacDonald, H.R. J. Exp. Med. (1977)
- Isolation, purification, and characterization of a mouse plasmacytoma cell surface glycoprotein involved in the resistance of the tumor cells to immune destruction. Rosenstein, Y., Theelen, M., Sánchez, I., Celis, E. J. Natl. Cancer Inst. (1985)
- Glucosamine-induced insulin resistance in 3T3-L1 adipocytes. Heart, E., Choi, W.S., Sung, C.K. Am. J. Physiol. Endocrinol. Metab. (2000)
- Structural gene products of the murine Ah complex. Differences in ontogenesis and glucosamine incorporation between liver microsomal cytochromes P1-450 and P-448 induced by polycyclic aromatic compounds. Negishi, M., Jensen, N.M., Garcia, G.S., Nebert, D.W. Eur. J. Biochem. (1981)
- Structure and affinity for antithrombin of heparan sulfate chains derived from basement membrane proteoglycans. Pejler, G., Bäckström, G., Lindahl, U., Paulsson, M., Dziadek, M., Fujiwara, S., Timpl, R. J. Biol. Chem. (1987)
- Combinatorial expression patterns of heparan sulfate sulfotransferases in zebrafish: I. The 3-O-sulfotransferase family. Cadwallader, A.B., Yost, H.J. Dev. Dyn. (2006)
- Glucosamine-induced insulin resistance is coupled to O-linked glycosylation of Munc18c. Chen, G., Liu, P., Thurmond, D.C., Elmendorf, J.S. FEBS Lett. (2003)
- Hexosamines stimulate leptin production in transgenic mice. McClain, D.A., Alexander, T., Cooksey, R.C., Considine, R.V. Endocrinology (2000)
- Enhanced synthesis and extracellular accumulation of hyaluronic acid during stimulation of quiescent human fibroblasts by mouse epidermal growth factor. Lembach, K.J. J. Cell. Physiol. (1976)
- Heparan sulfate synthesized by mouse embryonic stem cells deficient in NDST1 and NDST2 is 6-O-sulfated but contains no N-sulfate groups. Holmborn, K., Ledin, J., Smeds, E., Eriksson, I., Kusche-Gullberg, M., Kjellén, L. J. Biol. Chem. (2004)
- Role of glucosamine synthesis in the stimulation of TGF-alpha gene transcription by glucose and EGF. Roos, M.D., Han, I.O., Paterson, A.J., Kudlow, J.E. Am. J. Physiol. (1996)
- Cloning and partial characterization of the mouse glutamine:fructose-6-phosphate amidotransferase (GFAT) gene promoter. Sayeski, P.P., Wang, D., Su, K., Han, I.O., Kudlow, J.E. Nucleic Acids Res. (1997)
- Defective Akt activation is associated with glucose- but not glucosamine-induced insulin resistance. Nelson, B.A., Robinson, K.A., Buse, M.G. Am. J. Physiol. Endocrinol. Metab. (2002)
- Immunosuppressive effects of glucosamine. Ma, L., Rudert, W.A., Harnaha, J., Wright, M., Machen, J., Lakomy, R., Qian, S., Lu, L., Robbins, P.D., Trucco, M., Giannoukakis, N. J. Biol. Chem. (2002)
- Glucosamine abrogates the acute phase of experimental autoimmune encephalomyelitis by induction of Th2 response. Zhang, G.X., Yu, S., Gran, B., Rostami, A. J. Immunol. (2005)
- Characterization of a sustained-release delivery system for combined cytokine/peptide vaccination using a poly-N-acetyl glucosamine-based polymer matrix. Cole, D.J., Gattoni-Celli, S., McClay, E.F., Metcalf, J.S., Brown, J.M., Nabavi, N., Newton, D.A., Woolhiser, C.B., Wilson, M.C., Vournakis, J.N. Clin. Cancer Res. (1997)
- Glycoconjugates of murine tumor lines with different metastatic capacities. II. Diversity of glycolipid composition. Schwartz, R., Kniep, B., Müthing, J., Mühlradt, P.F. Int. J. Cancer (1985)