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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Skin Temperature

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Disease relevance of Skin Temperature


Psychiatry related information on Skin Temperature


High impact information on Skin Temperature


Chemical compound and disease context of Skin Temperature


Biological context of Skin Temperature


Anatomical context of Skin Temperature


Associations of Skin Temperature with chemical compounds


Gene context of Skin Temperature

  • The results show that in the mouse injection of both 5-HT1A and 5-HT1B receptor agonists has the ability to inhibit the tail-flick reflex without interfering with the tail skin temperature [32].
  • These results suggest not only that CGRP is closely related to the elevation of skin temperature but also that CGRP-induced responses are more affected by ovarian hormone deficiency [33].
  • Intravenous injection of CGRP (1-10 microg/kg), VIP (10-50 microg/kg) and SP (10-50 microg/kg) elevated the skin temperature in OVX and sham-operated rats in a dose-dependent manner [33].
  • Therefore, the increased number of CGRP receptors may be responsible for potentiation of exogenous alphaCGRP-induced elevation of skin temperature in OVX rats [34].
  • The changes in the tail-flick test were not due to changes in tail skin temperature since only minimal differences in the skin temperature were recorded between the groups injected with SP or vehicle [35].

Analytical, diagnostic and therapeutic context of Skin Temperature


  1. Relation between sympathetic vasoconstrictor activity and pain and hyperalgesia in complex regional pain syndromes: a case-control study. Baron, R., Schattschneider, J., Binder, A., Siebrecht, D., Wasner, G. Lancet (2002) [Pubmed]
  2. Coffee induced thermogenesis and skin temperature. Tagliabue, A., Terracina, D., Cena, H., Turconi, G., Lanzola, E., Montomoli, C. Int. J. Obes. Relat. Metab. Disord. (1994) [Pubmed]
  3. The second thoracic sympathetic ganglion determines palm skin temperature in patients with essential palmar hyperhidrosis. Wong, C.W. J. Auton. Nerv. Syst. (1997) [Pubmed]
  4. Effects of cutaneous histamine application in patients with sympathetic reflex dystrophy. Birklein, F., Claus, D., Riedl, B., Neundörfer, B., Handwerker, H.O. Muscle Nerve (1997) [Pubmed]
  5. Voluntary muscle activation is impaired by core temperature rather than local muscle temperature. Thomas, M.M., Cheung, S.S., Elder, G.C., Sleivert, G.G. J. Appl. Physiol. (2006) [Pubmed]
  6. The effects of food deprivation on beta-adrenergic responsiveness in male rats. Barney, C.C., Rutt, D.A., Katovich, M.J. Can. J. Physiol. Pharmacol. (1983) [Pubmed]
  7. Supersensitivity to the antinociceptive effect of a 5-HT1 receptor agonist after lesion of raphe-spinal serotonergic neurones. Eide, P.K., Hole, K., Broch, O.J. Pharmacol. Toxicol. (1992) [Pubmed]
  8. Controlled trial of nifedipine in the treatment of Raynaud's phenomenon. Smith, C.D., McKendry, R.J. Lancet (1982) [Pubmed]
  9. Nicotinic acid and skin temperature. Livingstone, S.D., Kuehn, L.A. Lancet (1981) [Pubmed]
  10. Facial skin temperature and the chlorpropamide/alcohol flush in diabetics. Radder, J.K., Box, M.C., Lemkes, H.H. Lancet (1980) [Pubmed]
  11. Trazodone-oral cocaine interactions. Rowbotham, M.C., Jones, R.T., Benowitz, N.L., Jacob, P. Arch. Gen. Psychiatry (1984) [Pubmed]
  12. Dissociation of thermoregulation in cats with cytotoxic pontine lesions. Amini-Sereshki, L. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  13. Spinal neurokinin3 receptors mediate thermal but not mechanical hyperalgesia via nitric oxide. Linden, D.R., Seybold, V.S. Pain (1999) [Pubmed]
  14. Hematologic changes during and after cardiopulmonary bypass and their relationship to the bleeding time and nonsurgical blood loss. Khuri, S.F., Wolfe, J.A., Josa, M., Axford, T.C., Szymanski, I., Assousa, S., Ragno, G., Patel, M., Silverman, A., Park, M. J. Thorac. Cardiovasc. Surg. (1992) [Pubmed]
  15. Effect of hypoxic breathing on cutaneous temperature recovery in man. Fahim, M. International journal of biometeorology. (1992) [Pubmed]
  16. Chlorpropamide-alcohol flush: significance of body weight, sex and serum chlorpropamide level. Groop, L., Eriksson, C.J., Wåhlin-Boll, E., Melander, A. Eur. J. Clin. Pharmacol. (1984) [Pubmed]
  17. Supplementation of nicotinic acid for lactating Holstein cows under heat stress conditions. Di Costanzo, A., Spain, J.N., Spiers, D.E. J. Dairy Sci. (1997) [Pubmed]
  18. Roles of chlorpropamide, alcohol and acetaldehyde in determining the chlorpropamide-alcohol flush. Groop, L., Eriksson, C.J., Huupponen, R., Ylikahri, R., Pelkonen, R. Diabetologia (1984) [Pubmed]
  19. Cotinine disposition and effects. Benowitz, N.L., Kuyt, F., Jacob, P., Jones, R.T., Osman, A.L. Clin. Pharmacol. Ther. (1983) [Pubmed]
  20. Additive cardiovascular effects of nicotine and ethanol. Benowitz, N.L., Jones, R.T., Jacob, P. Clin. Pharmacol. Ther. (1986) [Pubmed]
  21. Direct angiotensin converting enzyme inhibitor-mediated venodilation. Zarnke, K.B., Feldman, R.D. Clin. Pharmacol. Ther. (1996) [Pubmed]
  22. Biofeedback-assisted relaxation in type 2 diabetes. McGinnis, R.A., McGrady, A., Cox, S.A., Grower-Dowling, K.A. Diabetes Care (2005) [Pubmed]
  23. Effect of insulin concentration, subcutaneous fat thickness and skin temperature on subcutaneous insulin absorption in healthy subjects. Sindelka, G., Heinemann, L., Berger, M., Frenck, W., Chantelau, E. Diabetologia (1994) [Pubmed]
  24. Regional intravenous guanethidine vs. stellate ganglion block in reflex sympathetic dystrophies: a randomized trial. Bonelli, S., Conoscente, F., Movilia, P.G., Restelli, L., Francucci, B., Grossi, E. Pain (1983) [Pubmed]
  25. Analysis of circadian and ultradian rhythms of skin surface properties of face and forearm of healthy women. Le Fur, I., Reinberg, A., Lopez, S., Morizot, F., Mechkouri, M., Tschachler, E. J. Invest. Dermatol. (2001) [Pubmed]
  26. Temperature-sensitive adenosine-mediated vasoconstriction in the skin microcirculation. Stojanov, I., Proctor, K.G. J. Pharmacol. Exp. Ther. (1990) [Pubmed]
  27. Evidence for the participation of glutamate in reflexes involving afferent, substance P-containing nerve fibres in the rat. Juránek, I., Lembeck, F. Br. J. Pharmacol. (1996) [Pubmed]
  28. Efficacy and tolerability of a selective alpha(2C)-adrenergic receptor blocker in recovery from cold-induced vasospasm in scleroderma patients: a single-center, double-blind, placebo-controlled, randomized crossover study. Wise, R.A., Wigley, F.M., White, B., Leatherman, G., Zhong, J., Krasa, H., Kambayashi, J., Orlandi, C., Czerwiec, F.S. Arthritis Rheum. (2004) [Pubmed]
  29. Hypothermia-induced reversible platelet dysfunction. Valeri, C.R., Feingold, H., Cassidy, G., Ragno, G., Khuri, S., Altschule, M.D. Ann. Surg. (1987) [Pubmed]
  30. Response to cooling temperature in infants born at an altitude of 4,330 meters. Frappell, P.B., León-Velarde, F., Aguero, L., Mortola, J.P. Am. J. Respir. Crit. Care Med. (1998) [Pubmed]
  31. The influence of intrinsic sympathomimetic activity and beta-1 receptor selectivity on the recovery of finger skin temperature after finger cooling in normotensive subjects. Lenders, J.W., Salemans, J., de Boo, T., Lemmens, W.A., Thien, T., van't Laar, A. Clin. Pharmacol. Ther. (1986) [Pubmed]
  32. The role of spinal cord 5-HT1A and 5-HT1B receptors in the modulation of a spinal nociceptive reflex. Eide, P.K., Joly, N.M., Hole, K. Brain Res. (1990) [Pubmed]
  33. Effects of the vasoactive neuropeptides calcitonin gene-related peptide, substance P and vasoactive intestinal polypeptide on skin temperature in ovariectomized rats. Noguchi, M., Yuzurihara, M., Ikarashi, Y. Neuropeptides (2002) [Pubmed]
  34. Up-regulation of calcitonin gene-related peptide receptors underlying elevation of skin temperature in ovariectomized rats. Noguchi, M., Ikarashi, Y., Yuzurihara, M., Mizoguchi, K., Kurauchi, K., Chen, J.T., Ishige, A. J. Endocrinol. (2002) [Pubmed]
  35. Interactions between serotonin and substance P in the spinal regulation of nociception. Eide, P.K., Hole, K. Brain Res. (1991) [Pubmed]
  36. Naloxone increases blood flow in the human hand. Archer, A.G., Benroubi, M., Pyke, D.A., Wiles, P.G. J. Physiol. (Lond.) (1985) [Pubmed]
  37. Vascular abnormalities in acute reflex sympathetic dystrophy (CRPS I): complete inhibition of sympathetic nerve activity with recovery. Wasner, G., Heckmann, K., Maier, C., Baron, R. Arch. Neurol. (1999) [Pubmed]
  38. The effect of noradrenaline and 5-hydroxytryptamine injected into a lateral cerebral ventricle, on thermoregulation in the new-born lamb. Cooper, K.E., Pittman, Q.J., Veale, W.L. J. Physiol. (Lond.) (1976) [Pubmed]
  39. Assessment of rheumatoid inflammation in the knee joint. A reappraisal. Paterson, J., Watson, W.S., Teasdale, E., Evans, A.L., Newman, P., James, W.B., Pitkeathly, D.A. Ann. Rheum. Dis. (1978) [Pubmed]
  40. Haemodynamic effects of intra-arterial and intravenous administration of prostaglandin E1 in patients with peripheral arterial disease. Hirai, M., Nakayama, R. The British journal of surgery. (1986) [Pubmed]
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