Gene Review:
Mme - membrane metallo-endopeptidase
Rattus norvegicus
Synonyms:
Atriopeptidase, CD10, Enkephalinase, NEP, Nep, ...
- Relationship between the contents of adrenomedullin and distributions of neutral endopeptidase in blood and tissues of spontaneously hypertensive rats. Jiang, W., Jiang, H.F., Pan, C.S., Cai, D.Y., Qi, Y.F., Pang, Y.Z., Tang, C.S. Hypertens. Res. (2004)
- Relationship between contents of adrenomedullin and distributions of neutral endopeptidase in blood and tissues of rats in septic shock. Jiang, W., Jiang, H.F., Cai, D.Y., Pan, C.S., Qi, Y.F., Pang, Y.Z., Tang, C.S. Regul. Pept. (2004)
- Substance P and neutral endopeptidase in development of acute respiratory distress syndrome following fire smoke inhalation. Wong, S.S., Sun, N.N., Lantz, R.C., Witten, M.L. Am. J. Physiol. Lung Cell Mol. Physiol. (2004)
- Linkage and microarray analyses of susceptibility genes in ACI/Seg rats: a model for prostate cancers in the aged. Yamashita, S., Suzuki, S., Nomoto, T., Kondo, Y., Wakazono, K., Tsujino, Y., Sugimura, T., Shirai, T., Homma, Y., Ushijima, T. Cancer Res. (2005)
- Effect of mixed (RB 38A) and selective (RB 38B) inhibitors of enkephalin degrading enzymes on a model of depression in the rat. Tejedor-Real, P., Micó, J.A., Maldonado, R., Roques, B.P., Gibert-Rahola, J. Biol. Psychiatry (1993)
- Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder. Synthesis and activity of functionalized glutaramides. Pryde, D.C., Maw, G.N., Planken, S., Platts, M.Y., Sanderson, V., Corless, M., Stobie, A., Barber, C.G., Russell, R., Foster, L., Barker, L., Wayman, C., Van Der Graaf, P., Stacey, P., Morren, D., Kohl, C., Beaumont, K., Coggon, S., Tute, M. J. Med. Chem. (2006)
- Amelioration of naloxone-precipitated opioid withdrawal symptoms by peripheral administration of the enkephalinase inhibitor acetorphan. Livingston, S.J., Sewell, R.D., Rooney, K.F., Smith, H.J. Psychopharmacology (Berl.) (1988)
- Effects of SCH 32615, an enkephalinase inhibitor, on D-1 and D-2 dopamine receptor-mediated behaviors. Marin, C., Chase, T.N. Neuropharmacology (1995)
- Importance of delta opioid receptors in maintaining high alcohol drinking. Froehlich, J.C., Zweifel, M., Harts, J., Lumeng, L., Li, T.K. Psychopharmacology (Berl.) (1991)
- Selective protection of methionine enkephalin released from brain slices by enkephalinase inhibition. Patey, G., De La Baume, S., Schwartz, J.C., Gros, C., Roques, B., Fournie-Zaluski, M.C., Soroca-Lucas, E. Science (1981)
- Neutral endopeptidase and kininase II mediate glucocorticoid inhibition of neurogenic inflammation in the rat trachea. Piedimonte, G., McDonald, D.M., Nadel, J.A. J. Clin. Invest. (1991)
- Dual ACE and NEP inhibitor MDL-100,240 prevents and regresses severe angiotensin II-dependent hypertension partially through bradykinin type 2 receptor. Rossi, G.P., Cavallin, M., Rizzoni, D., Bova, S., Mazzocchi, G., Agabiti-Rosei, E., Nussdorfer, G.G., Pessina, A.C. J. Hypertens. (2002)
- The vasopeptidase inhibitor AVE7688 ameliorates Type 2 diabetic nephropathy. Schäfer, S., Linz, W., Vollert, H., Biemer-Daub, G., Rütten, H., Bleich, M., Busch, A.E. Diabetologia (2004)
- Pulmonary and renal neutral endopeptidase EC 3.4.24.11 in rats with experimental heart failure. Abassi, Z.A., Kotob, S., Golomb, E., Pieruzzi, F., Keiser, H.R. Hypertension (1995)
- Dual inhibition of neutral endopeptidase and angiotensin-converting enzyme in rats with hypertension and diabetes mellitus. Tikkanen, T., Tikkanen, I., Rockell, M.D., Allen, T.J., Johnston, C.I., Cooper, M.E., Burrell, L.M. Hypertension (1998)
- Dual angiotensin-converting enzyme/neutral endopeptidase inhibition on cardiac and renal fibrosis and inflammation in DOCA-salt hypertensive rats. Pu, Q., Amiri, F., Gannon, P., Schiffrin, E.L. J. Hypertens. (2005)
- Identification of the active-site arginine in rat neutral endopeptidase 24.11 (enkephalinase) as arginine 102 and analysis of a glutamine 102 mutant. Bateman, R.C., Jackson, D., Slaughter, C.A., Unnithan, S., Chai, Y.G., Moomaw, C., Hersh, L.B. J. Biol. Chem. (1989)
- Molecular cloning and amino acid sequence of rat enkephalinase. Malfroy, B., Schofield, P.R., Kuang, W.J., Seeburg, P.H., Mason, A.J., Henzel, W.J. Biochem. Biophys. Res. Commun. (1987)
- Intracardiac expression of neutral endopeptidase. Raizada, V., Luo, W., Skipper, B.J., McGuire, P.G. Mol. Cell. Biochem. (2002)
- The first preclinical pharmacotoxicological safety assessment of CGS 35601, a triple vasopeptidase inhibitor, in chronically instrumented, conscious, and unrestrained spontaneously hypertensive rats. Daull, P., Lepage, R., Benrezzak, O., Cayer, J., Beaudoin, M., Belleville, K., Blouin, A., Sirois, P., Nantel, F., Jeng, A.Y., Battistini, B. Drug and chemical toxicology. (2006)
- Triple VPI CGS 35601 reduces high blood pressure in low-renin, high-salt Dahl salt-sensitive rats. Daull, P., Blouin, A., Belleville, K., Beaudoin, M., Arsenault, D., Leonard, H., Sirois, P., Nantel, F., Jeng, A.Y., Battistini, B. Exp. Biol. Med. (Maywood) (2006)
- Ascorbic acid decreases neutral endopeptidase activity in cultured osteoblastic cells. Schmid, C., Ghirlanda-Keller, C., Gosteli-Peter, M. Regul. Pept. (2005)
- Omapatrilat: a unique new agent for the treatment of cardiovascular disease. Nawarskas, J.J., Anderson, J.R. Heart disease (Hagerstown, Md.) (2000)
- Hypertonic saline increases vascular permeability in the rat trachea by producing neurogenic inflammation. Umeno, E., McDonald, D.M., Nadel, J.A. J. Clin. Invest. (1990)
- Rat endothelin-converting enzyme-1 forms a dimer through Cys412 with a similar catalytic mechanism and a distinct substrate binding mechanism compared with neutral endopeptidase-24.11. Shimada, K., Takahashi, M., Turner, A.J., Tanzawa, K. Biochem. J. (1996)
- Fluorescent histochemical localization of neutral endopeptidase-24.11 (enkephalinase) in the rat spinal cord. Back, S.A., Gorenstein, C. J. Comp. Neurol. (1989)
- Assessment of the role of "enkephalinase" in cholecystokinin inactivation. Zuzel, K.A., Rose, C., Schwartz, J.C. Neuroscience (1985)
- The natriuretic mechanisms of neutral endopeptidase inhibitor in rats. Shimamoto, K., Ura, N., Iimura, O. Braz. J. Med. Biol. Res. (1994)
- Androgen-induced growth inhibition of androgen receptor expressing androgen-independent prostate cancer cells is mediated by increased levels of neutral endopeptidase. Shen, R., Sumitomo, M., Dai, J., Harris, A., Kaminetzky, D., Gao, M., Burnstein, K.L., Nanus, D.M. Endocrinology (2000)
- Tachykinin receptor and neutral endopeptidase gene expression in the rat uterus: characterization and regulation in response to ovarian steroid treatment. Pinto, F.M., Armesto, C.P., Magraner, J., Trujillo, M., Martín, J.D., Candenas, M.L. Endocrinology (1999)
- Neuronal localization of the neutral endopeptidase 'enkephalinase' in rat brain revealed by lesions and autoradiography. Waksman, G., Hamel, E., Delay-Goyet, P., Roques, B.P. EMBO J. (1986)
- Autoradiographic comparison of the distribution of the neutral endopeptidase "enkephalinase" and of mu and delta opioid receptors in rat brain. Waksman, G., Hamel, E., Fournié-Zaluski, M.C., Roques, B.P. Proc. Natl. Acad. Sci. U.S.A. (1986)
- Neutral endopeptidase in the heart. Neutral endopeptidase inhibition prevents isoproterenol-induced myocardial hypoperfusion in rats by reducing bradykinin degradation. Piedimonte, G., Nadel, J.A., Long, C.S., Hoffman, J.I. Circ. Res. (1994)
- Electron microscopic localization of immunoreactive enkephalinase (EC 3.4.24.11) in the neostriatum of the rat. Marcel, D., Pollard, H., Verroust, P., Schwartz, J.C., Beaudet, A. J. Neurosci. (1990)