Gene Review:
Ntrk1 - neurotrophic tyrosine kinase, receptor,...
Rattus norvegicus
Synonyms:
High affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, Slow nerve growth factor receptor, Trk, Trk-A, ...
Young,
Stone,
Hunt,
Yoshino,
Chao,
Venstrom,
Beyna,
Chen,
Lee,
Akhondzadeh,
Saragovi,
Berardi,
Hasenöhrl,
Valletta,
Shinohara,
Söderstróm,
Huang,
Pizzorusso,
Kowal,
Wu,
Waite,
Mobley,
Rajagopal,
Ebendal,
Kurihara,
Parada,
Huston,
Delcroix,
Reichardt,
Rossi,
Arévalo,
Viegi,
Shiba,
Maffei,
Mohammed,
Liebl,
Takeda,
- Differential cross-regulation of TrkA and TrkC tyrosine kinase receptors with p75. Ivanisevic, L., Banerjee, K., Saragovi, H.U. Oncogene (2003)
- Cyclophosphamide induced cystitis alters neurotrophin and receptor tyrosine kinase expression in pelvic ganglia and bladder. Murray, E., Malley, S.E., Qiao, L.Y., Hu, V.Y., Vizzard, M.A. J. Urol. (2004)
- Regulation of Trk receptors following contusion of the rat spinal cord. Liebl, D.J., Huang, W., Young, W., Parada, L.F. Exp. Neurol. (2001)
- Changes in retinal expression of neurotrophins and neurotrophin receptors induced by ocular hypertension. Rudzinski, M., Wong, T.P., Saragovi, H.U. J. Neurobiol. (2004)
- Neurotrophins in cultured cells from periodontal tissues. Kurihara, H., Shinohara, H., Yoshino, H., Takeda, K., Shiba, H. J. Periodontol. (2003)
- Progression of age-associated cognitive impairment correlates with quantitative and qualitative loss of TrkA receptor protein in nucleus basalis and cortex. Saragovi, H.U. J. Neurochem. (2005)
- TrkA activation in the rat visual cortex by antirat trkA IgG prevents the effect of monocular deprivation. Pizzorusso, T., Berardi, N., Rossi, F.M., Viegi, A., Venstrom, K., Reichardt, L.F., Maffei, L. Eur. J. Neurosci. (1999)
- Reciprocal changes in expression of mRNA for nerve growth factor and its receptors TrkA and LNGFR in brain of aged rats in relation to maze learning deficits. Hasenöhrl, R.U., Söderstróm, S., Mohammed, A.H., Ebendal, T., Huston, J.P. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. (1997)
- Expression of Trk isoforms in brain regions and in the striatum of patients with Alzheimer's disease. Dubus, P., Faucheux, B., Boissière, F., Groppi, A., Vital, C., Vital, A., Agid, Y., Hirsch, E.C., Merlio, J.P. Exp. Neurol. (2000)
- Lithium increases nerve growth factor levels in the rat hippocampus in an animal model of mania. Frey, B.N., Andreazza, A.C., Rosa, A.R., Martins, M.R., Valvassori, S.S., Réus, G.Z., Hatch, J.P., Quevedo, J., Kapczinski, F. Behavioural pharmacology. (2006)
- Neurotrophin-evoked rapid excitation through TrkB receptors. Kafitz, K.W., Rose, C.R., Thoenen, H., Konnerth, A. Nature (1999)
- Asymmetric membrane ganglioside sialidase activity specifies axonal fate. Da Silva, J.S., Hasegawa, T., Miyagi, T., Dotti, C.G., Abad-Rodriguez, J. Nat. Neurosci. (2005)
- Cell survival through Trk neurotrophin receptors is differentially regulated by ubiquitination. Arévalo, J.C., Waite, J., Rajagopal, R., Beyna, M., Chen, Z.Y., Lee, F.S., Chao, M.V. Neuron (2006)
- Evidence in support of signaling endosome-based retrograde survival of sympathetic neurons. Ye, H., Kuruvilla, R., Zweifel, L.S., Ginty, D.D. Neuron (2003)
- NGF signaling in sensory neurons: evidence that early endosomes carry NGF retrograde signals. Delcroix, J.D., Valletta, J.S., Wu, C., Hunt, S.J., Kowal, A.S., Mobley, W.C. Neuron (2003)
- Neurotrophins protect against cytosine arabinoside-induced apoptosis of immature rat cerebellar neurons. Leeds, P., Leng, Y., Chalecka-Franaszek, E., Chuang, D.M. Neurochem. Int. (2005)
- Effect of amyloid peptides on the increase in TrkA receptor expression induced by nicotine in vitro and in vivo. Li, X.D., Arias, E., Jonnala, R.R., Mruthinti, S., Buccafusco, J.J. J. Mol. Neurosci. (2005)
- TrkA induces differentiation but not apoptosis in C6-2B glioma cells. Pflug, B.R., Colangelo, A.M., Tornatore, C., Mocchetti, I. J. Neurosci. Res. (2001)
- P2Y2 and TrkA receptors interact with Src family kinase for neuronal differentiation. Arthur, D.B., Akassoglou, K., Insel, P.A. Biochem. Biophys. Res. Commun. (2006)
- Regulated neurotrophin receptor responsiveness during neuronal migrationand early differentiation. Knüsel, B., Rabin, S.J., Hefti, F., Kaplan, D.R. J. Neurosci. (1994)
- Distinctive features of Trk neurotrophin receptor transactivation by G protein-coupled receptors. Lee, F.S., Rajagopal, R., Chao, M.V. Cytokine Growth Factor Rev. (2002)
- Mutagenesis identifies amino-terminal residues of nerve growth factor necessary for Trk receptor binding and biological activity. Shih, A., Laramee, G.R., Schmelzer, C.H., Burton, L.E., Winslow, J.W. J. Biol. Chem. (1994)
- Pan-neurotrophin 1: a genetically engineered neurotrophic factor displaying multiple specificities in peripheral neurons in vitro and in vivo. Ilag, L.L., Curtis, R., Glass, D., Funakoshi, H., Tobkes, N.J., Ryan, T.E., Acheson, A., Lindsay, R.M., Persson, H., Yancopoulos, G.D. Proc. Natl. Acad. Sci. U.S.A. (1995)
- p75 and TrkA receptor signaling independently regulate amyloid precursor protein mRNA expression, isoform composition, and protein secretion in PC12 cells. Rossner, S., Ueberham, U., Schliebs, R., Perez-Polo, J.R., Bigl, V. J. Neurochem. (1998)
- Role of neurotrophins and neurotrophin receptors in rat conjunctival goblet cell secretion and proliferation. Ríos, J.D., Ghinelli, E., Gu, J., Hodges, R.R., Dartt, D.A. Invest. Ophthalmol. Vis. Sci. (2007)
- Gangliosides activate Trk receptors by inducing the release of neurotrophins. Rabin, S.J., Bachis, A., Mocchetti, I. J. Biol. Chem. (2002)
- Brain-derived neurotrophic factor binding to the p75 neurotrophin receptor reduces TrkA signaling while increasing serine phosphorylation in the TrkA intracellular domain. MacPhee, I.J., Barker, P.A. J. Biol. Chem. (1997)
- Down-regulation of the neurotrophin receptor TrkB following ligand binding. Evidence for an involvement of the proteasome and differential regulation of TrkA and TrkB. Sommerfeld, M.T., Schweigreiter, R., Barde, Y.A., Hoppe, E. J. Biol. Chem. (2000)
- Reciprocal modulation of TrkA and p75NTR affinity states is mediated by direct receptor interactions. Ross, G.M., Shamovsky, I.L., Lawrance, G., Solc, M., Dostaler, S.M., Weaver, D.F., Riopelle, R.J. Eur. J. Neurosci. (1998)
- Interaction of Mint2 with TrkA is involved in regulation of nerve growth factor-induced neurite outgrowth. Zhang, Y., Wang, Y.G., Zhang, Q., Liu, X.J., Liu, X., Jiao, L., Zhu, W., Zhang, Z.H., Zhao, X.L., He, C. J. Biol. Chem. (2009)
- Brain-derived neurotrophic factor (BDNF) mediates bone morphogenetic protein-2 (BMP-2) effects on cultured striatal neurones. Gratacòs, E., Checa, N., Pérez-Navarro, E., Alberch, J. J. Neurochem. (2001)
- Pancreatic acinar AR42J cells express functional nerve growth factor receptors. Miralles, F., Czernichow, P., Scharfmann, R. J. Endocrinol. (1999)
- Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor. Jung, K.M., Tan, S., Landman, N., Petrova, K., Murray, S., Lewis, R., Kim, P.K., Kim, D.S., Ryu, S.H., Chao, M.V., Kim, T.W. J. Biol. Chem. (2003)
- Expression of mRNA encoding neurotrophins and neurotrophin receptors in rat thymus, spleen tissue and immunocompetent cells. Regulation of neurotrophin-4 mRNA expression by mitogens and leukotriene B4. Laurenzi, M.A., Barbany, G., Timmusk, T., Lindgren, J.A., Persson, H. Eur. J. Biochem. (1994)
- The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA. Saxena, S., Bucci, C., Weis, J., Kruttgen, A. J. Neurosci. (2005)
- NGF and neurotrophin-3 both activate TrkA on sympathetic neurons but differentially regulate survival and neuritogenesis. Belliveau, D.J., Krivko, I., Kohn, J., Lachance, C., Pozniak, C., Rusakov, D., Kaplan, D., Miller, F.D. J. Cell Biol. (1997)
- Prevention of muscimol-induced long-term depression by brain-derived neurotrophic factor. Akhondzadeh, S., Stone, T. Prog. Neuropsychopharmacol. Biol. Psychiatry (1999)
- Mixed-lineage kinase inhibitors require the activation of Trk receptors to maintain long-term neuronal trophism and survival. Wang, L.H., Paden, A.J., Johnson, E.M. J. Pharmacol. Exp. Ther. (2005)
- Retinoic acid induces BDNF responsiveness of sympathetic neurons by alteration of Trk neurotrophin receptor expression. Kobayashi, M., Kurihara, K., Matsuoka, I. FEBS Lett. (1994)
- Effect of anti-NGF on ovarian expression of alpha1- and beta2-adrenoceptors, TrkA, p75NTR, and tyrosine hydroxylase in rats with steroid-induced polycystic ovaries. Manni, L., Holmäng, A., Cajander, S., Lundeberg, T., Aloe, L., Stener-Victorin, E. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2006)
- Neurotrophins regulate the function of cultured microglia. Nakajima, K., Kikuchi, Y., Ikoma, E., Honda, S., Ishikawa, M., Liu, Y., Kohsaka, S. Glia (1998)
- Association of the atypical protein kinase C-interacting protein p62/ZIP with nerve growth factor receptor TrkA regulates receptor trafficking and Erk5 signaling. Geetha, T., Wooten, M.W. J. Biol. Chem. (2003)