Gene Review:
CGA - glycoprotein hormones, alpha polypeptide
Homo sapiens
Synonyms:
Anterior pituitary glycoprotein hormones common subunit alpha, CG-ALPHA, CG-alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, ...
- CGA gene (coding for the alpha subunit of glycoprotein hormones) overexpression in ER alpha-positive prostate tumors. Bièche, I., Latil, A., Parfait, B., Vidaud, D., Laurendeau, I., Lidereau, R., Cussenot, O., Vidaud, M. Eur. Urol. (2002)
- Immunocytochemical evaluation of human esophageal neoplasms and preneoplastic lesions for beta-chorionic gonadotropin, placental lactogen, alpha-fetoprotein, carcinoembryonic antigen, and nonspecific cross-reacting antigen. Burg-Kurland, C.L., Purnell, D.M., Combs, J.W., Hillman, E.A., Harris, C.C., Trump, B.F. Cancer Res. (1986)
- Patterns of seminoma tissue markers and deletions. Yamamoto, H., Rudén, U., Ljungdahl-Ståhle, E., Brehmer-Andersson, E., Hirano, K., Hisazumi, H., Stigbrand, T., Wahren, B. Int. J. Cancer (1987)
- Hormonal state influences aspects of female mate choice in the Túngara Frog (Physalaemus pustulosus). Lynch, K.S., Crews, D., Ryan, M.J., Wilczynski, W. Hormones and behavior. (2006)
- Effect of platelet activating factor on embryonic development and implantation in the mouse. Fukuda, A.I., Breuel, K.F. Hum. Reprod. (1996)
- Annual rhythm and hormonal control of predatory behavior in female ferrets. Harrer, S., Schmidt, W.J. Physiol. Behav. (1986)
- Serum tumour markers in testicular and extragonadal germ cell malignancies. Klepp, O. Scand. J. Clin. Lab. Invest. Suppl. (1991)
- Herlitz's junctional epidermolysis bullosa is linked to mutations in the gene (LAMC2) for the gamma 2 subunit of nicein/kalinin (LAMININ-5). Aberdam, D., Galliano, M.F., Vailly, J., Pulkkinen, L., Bonifas, J., Christiano, A.M., Tryggvason, K., Uitto, J., Epstein, E.H., Ortonne, J.P. Nat. Genet. (1994)
- Ectopic production of chorionic gonadotropin and its subunits by islet-cell tumors. A specific marker for malignancy. Kahn, C.R., Rosen, S.W., Weintraub, B.D., Fajans, S.S., Gorden, P. N. Engl. J. Med. (1977)
- HCG stimulation of testicular LHRH-like activity. Sharpe, R.M., Fraser, H.M. Nature (1980)
- The CGA gene as new predictor of the response to endocrine therapy in ER alpha-positive postmenopausal breast cancer patients. Bièche, I., Parfait, B., Noguès, C., Andrieu, C., Vidaud, D., Spyratos, F., Lidereau, R., Vidaud, M. Oncogene (2001)
- The role of radioimmunodetection in the management of testicular cancer. Javadpour, N., Kim, E.E., DeLand, F.H., Salyer, J.R., Shah, U., Goldenberg, D.M. JAMA (1981)
- The prognostic value of CEA, beta HCG, AFP, CA125, CA19-9 and C-erb B-2, beta HCG immunohistochemistry in advanced colorectal cancer. Webb, A., Scott-Mackie, P., Cunningham, D., Norman, A., Andreyev, J., O'Brien, M., Bensted, J. Ann. Oncol. (1995)
- HCG, HPL, oestradiol, progesterone and AFP in serum in patients with threatened abortion. Kunz, J., Keller, P.J. British journal of obstetrics and gynaecology. (1976)
- False-positive and false-negative alpha-feto protein and human chorionic gonadotropin assays in testicular cancer: a double blind study. Javadpour, N., Soares, T. Cancer (1981)
- Recognition by the glycoprotein hormone-specific N-acetylgalactosaminetransferase is independent of hormone native conformation. Smith, P.L., Baenziger, J.U. Proc. Natl. Acad. Sci. U.S.A. (1990)
- Assignment of disulfide bonds in the alpha subunit of human chorionic gonadotropin. Mise, T., Bahl, O.P. J. Biol. Chem. (1980)
- Purification and characterization of recombinant human thyrotropin (TSH) isoforms produced by Chinese hamster ovary cells: the role of sialylation and sulfation in TSH bioactivity. Szkudlinski, M.W., Thotakura, N.R., Bucci, I., Joshi, L.R., Tsai, A., East-Palmer, J., Shiloach, J., Weintraub, B.D. Endocrinology (1993)
- Trophoblastic cells expressing human chorionic gonadotropin genes in peripheral blood of patients with trophoblastic disease. Taniguchi, R., Koizumi, T., Das, H., Chakraborty, S., Sugimoto, T., Hasegawa, K., Kono, M., Nishimura, R. Life Sci. (2000)
- In silico identification of breast cancer genes by combined multiple high throughput analyses. Shen, D., He, J., Chang, H.R. Int. J. Mol. Med. (2005)
- Alpha-fetoprotein and beta-human chorionic gonadotropin: their clinical significance as tumour markers. Gregory, J.J., Finlay, J.L. Drugs (1999)
- Distribution of tumor-associated antigens in the various histologic components of germ cell tumors of the testis. Jacobsen, G.K., Jacobsen, M., Clausen, P.P. Am. J. Surg. Pathol. (1981)
- Markers and characteristics of human SCLC cell lines. Neuroendocrine markers, classical tumor markers, and chromosomal characteristics of permanent human small cell lung cancer cell lines. Bepler, G., Jaques, G., Koehler, A., Gropp, C., Havemann, K. J. Cancer Res. Clin. Oncol. (1987)
- alpha-Fetoprotein (AFP), human chorionic gonadotropin (HCG), and carcinoembryonic antigen (CEA) demonstrated in the immature glands of mediastinal teratocarcinoma: a case report. Irie, T., Watanabe, H., Kawaoi, A., Takeuchi, J. Cancer (1982)
- Maternal serum alpha-fetoprotein levels in a triplet pregnancy with 2 papyraceous fetuses. Taubert, H.D., Bastert, G., Dericks-Tan, J.S. Arch. Gynecol. (1986)
- Studies on the disulfide bonds in human pituitary follicle-stimulating hormone. Fujiki, Y., Rathnam, P., Saxena, B.B. Biochim. Biophys. Acta (1980)
- Morphologic features of human chorionic gonadotropin- or alpha-fetoprotein-producing germ cell tumors of the central nervous system: histological heterogeneity and surgical meaning. Sugiyama, K., Arita, K., Tominaga, A., Hanaya, R., Taniguchi, E., Okamura, T., Itoh, Y., Yamasaki, F., Kurisu, K. Brain tumor pathology. (2001)
- Topographic analysis of the alpha-subunit of human follicle-stimulating hormone using site-specific antipeptide antisera. Weiner, R.S., Andersen, T.T., Dias, J.A. Endocrinology (1990)
- HCG binding to the testicular LH receptor is similar in fertile, subfertile, and infertile stallions. Motton, D.D., Roser, J.F. J. Androl. (1997)
- Immunohistochemical localization of the LH/HCG receptor in human ovary: HCG enhances cell surface expression of LH/HCG receptor on luteinizing granulosa cells in vitro. Takao, Y., Honda, T., Ueda, M., Hattori, N., Yamada, S., Maeda, M., Fujiwara, H., Mori, T., Wimalasena, J. Mol. Hum. Reprod. (1997)
- First-trimester biochemical screening for fetal chromosome abnormalities and neural tube defects. Aitken, D.A., McCaw, G., Crossley, J.A., Berry, E., Connor, J.M., Spencer, K., Macri, J.N. Prenat. Diagn. (1993)
- Vasoactive intestinal peptide increases intracellular cAMP and gonadotropin-alpha gene activity in JEG-3 syncytial trophoblasts. Constraints posed by desensitization. Deutsch, P.J., Sun, Y., Kroog, G.S. J. Biol. Chem. (1990)
- c-Jun represses transcription of the human chorionic gonadotropin alpha and beta genes through distinct types of CREs. Pestell, R.G., Hollenberg, A.N., Albanese, C., Jameson, J.L. J. Biol. Chem. (1994)
- Epidermal growth factor stimulates secretion of human chorionic gonadotropin by cultured human choriocarcinoma cells. Benveniste, R., Speeg, K.V., Carpenter, G., Cohen, S., Lindner, J., Rabinowitz, D. J. Clin. Endocrinol. Metab. (1978)
- An immunohistochemical study of intracranial germ cell tumours. Yamagami, T., Handa, H., Yamashita, J., Okumura, T., Paine, J., Haebara, H., Furukawa, F. Acta neurochirurgica. (1987)
- The prognostic value of serum and immunohistochemical tumour markers in advanced gastric cancer. Webb, A., Scott-Mackie, P., Cunningham, D., Norman, A., Andreyev, J., O'Brien, M., Bensted, J. Eur. J. Cancer (1996)
- Simultaneous assays of cancer-associated antigens in various neoplastic disorders. Franchimont, P., Zangerle, P.F., Nogarede, J., Bury, J., Molter, F., Reuter, A., Hendrick, J.C., Collette, J. Cancer (1976)
- An immunohistochemical study of keratin, carcinoembryonic antigen, human chorionic gonadotropin and alpha-fetoprotein in lung cancer. Kimura, N., Ghandur-Mnaymen, L. Tohoku J. Exp. Med. (1985)
- Immunocytochemical localization of the subunits of glycoprotein hormones (LH, FSH, and TSH) in the bullfrog pituitary gland using monoclonal antibodies and polyclonal antiserum. Tanaka, S., Park, M.K., Hayashi, H., Hanaoka, Y., Wakabayashi, K., Kurosumi, K. Gen. Comp. Endocrinol. (1990)
- Alpha-fetoprotein (AFP) and human chorionic gonadotropin (HCG) in testicular germ cell tumours. A comparison of histologic and serologic occurrence of tumour markers. Jacobsen, G.K. Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology. (1983)
- Cloning and sequencing of feline thyrotropin (fTSH): heterodimeric and yoked constructs. Rayalam, S., Eizenstat, L.D., Hoenig, M., Ferguson, D.C. Domest. Anim. Endocrinol. (2006)