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Chemical Compound Review

Syntarpen     (2R,5R,6S)-6-[[3-(2- chlorophenyl)-5-methyl...

Synonyms: Orbenin, Tegopen, Cloxacilina, MCIPC, cloxacillin, ...
 
 
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Disease relevance of Syntarpen

 

Psychiatry related information on Syntarpen

 

High impact information on Syntarpen

 

Chemical compound and disease context of Syntarpen

  • Six hundred and twelve mouse plasmacytomas were screened for hapten binding by using eleven different bacteriophage-hapten conjugates (phage T4 conjugated with haptens NP, NIP, DIP, DNP,BOC-ABA-Tyr, ABA-NP, ABA-MIP, ABS-HOP, PAB-HOP, penicillin G, cloxacillin) [13].
  • The reversible inhibition of beta-lactamase I from Bacillus cereus by cloxacillin, methicillin, and nafcillin has been systematically investigated [14].
  • Moreover, by using beta-lactams which were readily hydrolyzed by the Pseudomonas aeruginosa class C chromosomal beta-lactamase, it was demonstrated that elimination of the mexAB-oprM-encoded efflux system greatly enhanced the abilities of cloxacillin and BRL42715 (but not clavulanate) to increase beta-lactam susceptibility [15].
  • Animals with catheter-induced endocarditis were infected intravenously with 10(5) CFU of Staphylococcus aureus S5 (MICs and minimal bactericidal concentrations of cloxacillin, ceftriaxone, and gentamicin, 0.5 and 2 microg/ml, 4 and 8 microg/ml, and 0.5 and 1 microg/ml, respectively) [16].
  • An unusual cephalosporinase in Achromobacter species was characterized biochemically; the enzyme had a pI of 8.1 and a molecular mass of 36,200 daltons, and it was not inhibited by p-chloromercuribenzoate or cloxacillin [17].
 

Biological context of Syntarpen

 

Anatomical context of Syntarpen

 

Associations of Syntarpen with other chemical compounds

 

Gene context of Syntarpen

 

Analytical, diagnostic and therapeutic context of Syntarpen

References

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