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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Population Groups

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Disease relevance of Population Groups


Psychiatry related information on Population Groups


High impact information on Population Groups

  • Low plasma beta-carotene levels averaging 8-12 micrograms/dl were observed among the population groups [11].
  • The average plasma retinol levels ranged from 24 to 27 micrograms/dl among the population groups, with 20-35% of the individuals having levels under 20 micrograms/dl [11].
  • SETTING: 2 public health department clinics in North Carolina. Participants: 121 adults who had recently emigrated from Vietnam to North Carolina and who were ethnic Vietnamese and ethnic Dega, a minority population group from the central highlands region of Vietnam [12].
  • In the same population group we have studied extensively in the past, we found a higher association of a TAP1 allele with IDDM than with any single HLA-DP allele but the risk was lower than with HLA-DQB1*0302 [13].
  • Apo J revealed a common two-allele polymorphism only in populations with African ancestry and was found to be monomorphic in all other population groups tested [14].

Chemical compound and disease context of Population Groups


Biological context of Population Groups


Anatomical context of Population Groups


Associations of Population Groups with chemical compounds


Gene context of Population Groups

  • BACKGROUND: Although CYP2D6 has been studied extensively in different population groups, relatively little is known for black Americans [34].
  • MICA, HLA-B haplotypic variation in five population groups of sub-Saharan African ancestry [35].
  • This approach allowed extrapolation of the recombinant clearance data to specific population groups and investigation of the role of "minor" forms like CYP3A5 and CYP2C19 in comparison to the most prolific CYP3A4 [36].
  • C4A alleles A*4, A*45, A*58, A*12, A*14, A*19 and the C4A*3 A*91 duplication were only found in the San/Khoi population group [37].
  • DNA samples of 2303 individuals from nine different population groups were screened for variant -175g-->t in the promoter region of the low-density lipoprotein receptor (LDLR) gene [38].

Analytical, diagnostic and therapeutic context of Population Groups

  • HLA-A, -B, -C, -DR, -DQ typing in a population group of Senegal: distribution of HLA antigens and HLA-DRB1*13 and DRB1*11 subtyping by PCR using sequence-specific primers (PCR-SSP) [39].
  • A randomized, double-blind study used 24-hour ambulatory blood pressure (BP) monitoring to compare the effects of 2 beta blockers, bisoprolol (10 to 20 mg; n = 107) and atenolol (50 to 100 mg; n = 96), administered once daily in 4 population groups [18].
  • When different population groups of tropical Venezuela were evaluated using ELISA based upon Toxocara excretory-secretory antigen (TcESA), solid-phase adsorption of the sera with extracts of a wide variety of non-homologous parasites revealed the existence of significant cross-reactivity [40].
  • A simple nonradioactive method of DNA typing for subsets of HLA-DR4: prevalence data on HLA-DR4 subsets in three diabetic population groups [41].
  • OBJECTIVE: To characterize the carotenoid content of selected components of the Mediterranean diet commonly eaten by Greek migrants to Melbourne, a population group maintaining a traditional dietary regimen, and who exhibit relatively high circulating carotenoid concentrations and low cardiovascular disease mortality [42].


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  15. Trace metal content of cerebral vessels in American Blacks, Caucasians and Nigerian Africans. Taylor, G.O., Williams, A.O., Resch, J.A., Barber, J.B., Jackson, M.A., Paulissen, G.A. Stroke (1975) [Pubmed]
  16. Beta-carotene levels in exfoliated mucosa cells of population groups at low and elevated risk for oral cancer. Stich, H.F., Hornby, A.P., Dunn, B.P. Int. J. Cancer (1986) [Pubmed]
  17. Goserelin: a review of its use in the treatment of early breast cancer in premenopausal and perimenopausal women. Cheer, S.M., Plosker, G.L., Simpson, D., Wagstaff, A.J. Drugs (2005) [Pubmed]
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  21. Breast milk composition in Ethiopian and Swedish mothers. I. Vitamin A and beta-carotene. Gebre-Medhin, M., Vahlquist, A., Hofvander, Y., Uppsäll, L., Vahlquist, B. Am. J. Clin. Nutr. (1976) [Pubmed]
  22. PPAR gamma and the treatment of insulin resistance. Olefsky, J.M., Saltiel, A.R. Trends Endocrinol. Metab. (2000) [Pubmed]
  23. Differential basal synthesis of Hsp70/Hsc70 contributes to interindividual variation in Hsp70/Hsc70 inducibility. Boshoff, T., Lombard, F., Eiselen, R., Bornman, J.J., Bachelet, M., Polla, B.S., Bornman, L. Cell. Mol. Life Sci. (2000) [Pubmed]
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  26. The association between HLA-A alleles and young Alu dimorphisms near the HLA-J, -H, and -F genes in workshop cell lines and Japanese and Australian populations. Dunn, D.S., Naruse, T., Inoko, H., Kulski, J.K. J. Mol. Evol. (2002) [Pubmed]
  27. Performance of glutaraldehyde-preserved porcine bioprosthesis as a mitral valve substitute in a young population group. Antunes, M.J., Santos, L.P. Ann. Thorac. Surg. (1984) [Pubmed]
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  29. Chromosomal polymorphisms of 1, 9, 16, and Y in 4 major ethnic groups: a large prenatal study. Hsu, L.Y., Benn, P.A., Tannenbaum, H.L., Perlis, T.E., Carlson, A.D. Am. J. Med. Genet. (1987) [Pubmed]
  30. Dietary intake and serum total cholesterol level: their relationship to different lifestyles in several Japanese populations. Ueshima, H., Iida, M., Shimamoto, T., Konishi, M., Tanigaki, M., Doi, M., Nakanishi, N., Takayama, Y., Ozawa, H., Komachi, Y. Circulation (1982) [Pubmed]
  31. Urinary excretion of nitrate, N-nitrosoproline, 3-methyladenine, and 7-methylguanine in a Colombian population at high risk for stomach cancer. Stillwell, W.G., Glogowski, J., Xu, H.X., Wishnok, J.S., Zavala, D., Montes, G., Correa, P., Tannenbaum, S.R. Cancer Res. (1991) [Pubmed]
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  35. MICA, HLA-B haplotypic variation in five population groups of sub-Saharan African ancestry. Tian, W., Boggs, D.A., Uko, G., Essiet, A., Inyama, M., Banjoko, B., Adewole, T., Ding, W.Z., Mohseni, M., Fritz, R., Chen, D.F., Palmer, L.J., Fraser, P.A. Genes Immun. (2003) [Pubmed]
  36. Utility of recombinant enzyme kinetics in prediction of human clearance: impact of variability, CYP3A5, and CYP2C19 on CYP3A4 probe substrates. Galetin, A., Brown, C., Hallifax, D., Ito, K., Houston, J.B. Drug Metab. Dispos. (2004) [Pubmed]
  37. C4 polymorphism and extended HLA haplotypes in Namibian San and Khoi and in South African Xhosa. Creemers, P.C., du Toit, E.D. Tissue Antigens (1996) [Pubmed]
  38. Allelic variation in the promoter region of the LDL receptor gene: analysis of an African-specific variant in the FP2 cis-acting regulatory element. Hoogendijk, C.F., Scholtz, C.L., Pimstone, S.M., Ehrenborg, E., Kastelein, J.J., Defesche, J.C., Thiart, R., du Plessis, L., de Villiers, J.N., Zaahl, M.G., Delport, R., Rubinsztein, D.C., Raffel, L.J., Grim, C.E., Mediene-Benchekor, S., Amouyel, P., Brousseau, T., Steyn, K., Lombard, C.J., Hayden, M.R., Kotze, M.J. Mol. Cell. Probes (2003) [Pubmed]
  39. HLA-A, -B, -C, -DR, -DQ typing in a population group of Senegal: distribution of HLA antigens and HLA-DRB1*13 and DRB1*11 subtyping by PCR using sequence-specific primers (PCR-SSP). Dieye, A., Diaw, M.L., Rogier, C., Trape, J.F., Sarthou, J.L. Tissue Antigens (1996) [Pubmed]
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  41. A simple nonradioactive method of DNA typing for subsets of HLA-DR4: prevalence data on HLA-DR4 subsets in three diabetic population groups. Ju, L.Y., Gu, X.F., Bardie, R., Krishnamoorthy, R., Charron, D. Hum. Immunol. (1991) [Pubmed]
  42. Identification and quantitation of major carotenoids in selected components of the Mediterranean diet: green leafy vegetables, figs and olive oil. Su, Q., Rowley, K.G., Itsiopoulos, C., O'Dea, K. European journal of clinical nutrition. (2002) [Pubmed]
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