Gene Review:
Eln - elastin
Mus musculus
Synonyms:
AI385707, AI480567, E030024M20Rik, Elastin, Tropoelastin, ...
- B-Myb represses elastin gene expression in aortic smooth muscle cells. Hofmann, C.S., Wang, X., Sullivan, C.P., Toselli, P., Stone, P.J., McLean, S.E., Mecham, R.P., Schreiber, B.M., Sonenshein, G.E. J. Biol. Chem. (2005)
- Spontaneous aortic aneurysms in blotchy mice. Andrews, E.J., White, W.J., Bullock, L.P. Am. J. Pathol. (1975)
- Gene expression profiling in lung tissues from mice exposed to cigarette smoke, lipopolysaccharide, or smoke plus lipopolysaccharide by inhalation. Meng, Q.R., Gideon, K.M., Harbo, S.J., Renne, R.A., Lee, M.K., Brys, A.M., Jones, R. Inhalation toxicology. (2006)
- Developmental adaptation of the mouse cardiovascular system to elastin haploinsufficiency. Faury, G., Pezet, M., Knutsen, R.H., Boyle, W.A., Heximer, S.P., McLean, S.E., Minkes, R.K., Blumer, K.J., Kovacs, A., Kelly, D.P., Li, D.Y., Starcher, B., Mecham, R.P. J. Clin. Invest. (2003)
- Elastin is an essential determinant of arterial morphogenesis. Li, D.Y., Brooke, B., Davis, E.C., Mecham, R.P., Sorensen, L.K., Boak, B.B., Eichwald, E., Keating, M.T. Nature (1998)
- Elastic fiber homeostasis requires lysyl oxidase-like 1 protein. Liu, X., Zhao, Y., Gao, J., Pawlyk, B., Starcher, B., Spencer, J.A., Yanagisawa, H., Zuo, J., Li, T. Nat. Genet. (2004)
- Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema. Morris, D.G., Huang, X., Kaminski, N., Wang, Y., Shapiro, S.D., Dolganov, G., Glick, A., Sheppard, D. Nature (2003)
- Fibulin-5/DANCE is essential for elastogenesis in vivo. Nakamura, T., Lozano, P.R., Ikeda, Y., Iwanaga, Y., Hinek, A., Minamisawa, S., Cheng, C.F., Kobuke, K., Dalton, N., Takada, Y., Tashiro, K., Ross Jr, J., Honjo, T., Chien, K.R. Nature (2002)
- Laminin regulates a tumor cell chemotaxis receptor through the laminin-binding integrin subunit alpha 6. Blood, C.H., Zetter, B.R. Cancer Res. (1993)
- Differential expression of elastin and alpha 1(I) collagen mRNA in mice with bleomycin-induced pulmonary fibrosis. Lucey, E.C., Ngo, H.Q., Agarwal, A., Smith, B.D., Snider, G.L., Goldstein, R.H. Lab. Invest. (1996)
- Elastin gene expression is upregulated during pulmonary fibrosis. Hoff, C.R., Perkins, D.R., Davidson, J.M. Connect. Tissue Res. (1999)
- Lysosomal cysteine proteases in atherosclerosis. Liu, J., Sukhova, G.K., Sun, J.S., Xu, W.H., Libby, P., Shi, G.P. Arterioscler. Thromb. Vasc. Biol. (2004)
- Pelvic organ prolapse in fibulin-5 knockout mice: pregnancy-induced changes in elastic fiber homeostasis in mouse vagina. Drewes, P.G., Yanagisawa, H., Starcher, B., Hornstra, I., Csiszar, K., Marinis, S.I., Keller, P., Word, R.A. Am. J. Pathol. (2007)
- The tissue distribution of murine Abcc6 (Mrp6) during embryogenesis indicates that the presence of Abcc6 in elastic tissues is not required for elastic fiber assembly. Beck, K., Dang, K., Boyd, C.D. J. Mol. Histol. (2005)
- Normal wound healing in mice deficient for fibulin-5, an elastin binding protein essential for dermal elastic fiber assembly. Zheng, Q., Choi, J., Rouleau, L., Leask, R.L., Richardson, J.A., Davis, E.C., Yanagisawa, H. J. Invest. Dermatol. (2006)
- Mapping of Col3a1 and Col6a3 to proximal murine chromosome 1 identifies conserved linkage of structural protein genes between murine chromosome 1 and human chromosome 2q. Schurr, E., Skamene, E., Morgan, K., Chu, M.L., Gros, P. Genomics (1990)
- Expression and accumulation of lysyl oxidase, elastin, and type I procollagen in human Menkes and mottled mouse fibroblasts. Gacheru, S., McGee, C., Uriu-Hare, J.Y., Kosonen, T., Packman, S., Tinker, D., Krawetz, S.A., Reiser, K., Keen, C.L., Rucker, R.B. Arch. Biochem. Biophys. (1993)
- Fibulin-5/DANCE has an elastogenic organizer activity that is abrogated by proteolytic cleavage in vivo. Hirai, M., Ohbayashi, T., Horiguchi, M., Okawa, K., Hagiwara, A., Chien, K.R., Kita, T., Nakamura, T. J. Cell Biol. (2007)
- Coordinate expression of fibulin-5/DANCE and elastin during lung injury repair. Kuang, P.P., Goldstein, R.H., Liu, Y., Rishikof, D.C., Jean, J.C., Joyce-Brady, M. Am. J. Physiol. Lung Cell Mol. Physiol. (2003)
- Induction of macrophage chemotaxis by aortic extracts of the mgR Marfan mouse model and a GxxPG-containing fibrillin-1 fragment. Guo, G., Booms, P., Halushka, M., Dietz, H.C., Ney, A., Stricker, S., Hecht, J., Mundlos, S., Robinson, P.N. Circulation (2006)
- Elastin induces myofibrillogenesis via a specific domain, VGVAPG. Karnik, S.K., Wythe, J.D., Sorensen, L., Brooke, B.S., Urness, L.D., Li, D.Y. Matrix Biol. (2003)
- Decreased lysyl oxidase activity in the aneurysm-prone, mottled mouse. Rowe, D.W., McGoodwin, E.B., Martin, G.R., Grahn, D. J. Biol. Chem. (1977)
- Topical tretinoin increases the tropoelastin and fibronectin content of photoaged hairless mouse skin. Schwartz, E., Kligman, L.H. J. Invest. Dermatol. (1995)
- A fluorometric assay for detection of lysyl oxidase enzyme activity in biological samples. Palamakumbura, A.H., Trackman, P.C. Anal. Biochem. (2002)
- Propranolol stimulates the crosslinking of matrix components in skin from the aneurysm-prone blotchy mouse. Brophy, C.M., Tilson, J.E., Tilson, M.D. J. Surg. Res. (1989)
- Autocrine growth factor regulation of lysyl oxidase expression in transformed fibroblasts. Palamakumbura, A.H., Sommer, P., Trackman, P.C. J. Biol. Chem. (2003)
- Developmental expression of latent transforming growth factor beta binding protein 2 and its requirement early in mouse development. Shipley, J.M., Mecham, R.P., Maus, E., Bonadio, J., Rosenbloom, J., McCarthy, R.T., Baumann, M.L., Frankfater, C., Segade, F., Shapiro, S.D. Mol. Cell. Biol. (2000)
- Macrophage expression of active MMP-9 induces acute plaque disruption in apoE-deficient mice. Gough, P.J., Gomez, I.G., Wille, P.T., Raines, E.W. J. Clin. Invest. (2006)
- Development of the aortic vessel wall as defined by vascular smooth muscle and extracellular matrix markers. Hungerford, J.E., Owens, G.K., Argraves, W.S., Little, C.D. Dev. Biol. (1996)
- Pharmacological modulation of the antioxidant enzymes activities and the concentration of peroxidation products in fibroblasts stimulated with elastin peptides. Gmiński, J., Weglarz, L., Drózdz, M., Goss, M. Gen. Pharmacol. (1991)
- Use of an intron polymorphism to localize the tropoelastin gene to mouse chromosome 5 in a region of linkage conservation with human chromosome 7. Wydner, K.S., Sechler, J.L., Boyd, C.D., Passmore, H.C. Genomics (1994)
- Extracellular matrix protein expression during mouse detrusor development. Smeulders, N., Woolf, A.S., Wilcox, D.T. J. Pediatr. Surg. (2003)
- Smad3 deficiency alters key structural elements of the extracellular matrix and mechanotransduction of wound closure. Arany, P.R., Flanders, K.C., Kobayashi, T., Kuo, C.K., Stuelten, C., Desai, K.V., Tuan, R., Rennard, S.I., Roberts, A.B. Proc. Natl. Acad. Sci. U.S.A. (2006)
- The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers. Thomassin, L., Werneck, C.C., Broekelmann, T.J., Gleyzal, C., Hornstra, I.K., Mecham, R.P., Sommer, P. J. Biol. Chem. (2005)
- Targeted disruption of fibulin-4 abolishes elastogenesis and causes perinatal lethality in mice. McLaughlin, P.J., Chen, Q., Horiguchi, M., Starcher, B.C., Stanton, J.B., Broekelmann, T.J., Marmorstein, A.D., McKay, B., Mecham, R., Nakamura, T., Marmorstein, L.Y. Mol. Cell. Biol. (2006)
- Reduced transplant arteriosclerosis in plasminogen-deficient mice. Moons, L., Shi, C., Ploplis, V., Plow, E., Haber, E., Collen, D., Carmeliet, P. J. Clin. Invest. (1998)