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Chemical Compound Review

Aminooxyacetate     2-aminooxyethanoic acid

Synonyms: AOAA, Lopac-A-4508, CHEMBL347862, AG-K-07535, CCG-204103, ...
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Disease relevance of Aminooxyacetic acid


Psychiatry related information on Aminooxyacetic acid


High impact information on Aminooxyacetic acid


Chemical compound and disease context of Aminooxyacetic acid


Biological context of Aminooxyacetic acid


Anatomical context of Aminooxyacetic acid


Associations of Aminooxyacetic acid with other chemical compounds


Gene context of Aminooxyacetic acid


Analytical, diagnostic and therapeutic context of Aminooxyacetic acid


  1. A gerbil model of cerebral ischemia suitable for drug evaluation. Jarrott, D.M., Domer, F.R. Stroke (1980) [Pubmed]
  2. Aminooxyacetic acid: correlation between biochemical effects, anticonvulsant action and toxicity in mice. Löscher, W., Frey, H.H. Biochem. Pharmacol. (1978) [Pubmed]
  3. Relationship between drug-induced increases of GABA levels in discrete brain areas and different pharmacological effects in rats. Löscher, W., Vetter, M. Biochem. Pharmacol. (1984) [Pubmed]
  4. Aminooxyacetic acid produces excitotoxic brain injury in neonatal rats. McDonald, J.W., Schoepp, D.D. Brain Res. (1993) [Pubmed]
  5. Studies of myocardial protection in the immature heart. II. Evidence for importance of amino acid metabolism in tolerance to ischemia. Julia, P., Young, H.H., Buckberg, G.D., Kofsky, E.R., Bugyi, H.I. J. Thorac. Cardiovasc. Surg. (1990) [Pubmed]
  6. Effect of intraperitoneally administered GABA on the locomotor activity of mice. Biswas, B., Carlsson, A. Psychopharmacology (Berl.) (1978) [Pubmed]
  7. GABAergic modulation of memory with regard to passive avoidance and conditioned suppression task in mice. Nabeshima, T., Noda, Y., Kameyama, T. Psychopharmacology (Berl.) (1988) [Pubmed]
  8. Gamma-aminobutyric acid controls the mouse hypothalamic-pituitary-testicular response to the presence of female. Naumenko, E.V., Serova, L.I. Pharmacol. Biochem. Behav. (1991) [Pubmed]
  9. Regulation of the cellular stress response by reactive electrophiles. The role of covalent binding and cellular thiols in transcriptional activation of the 70-kilodalton heat shock protein gene by nephrotoxic cysteine conjugates. Chen, Q., Yu, K., Stevens, J.L. J. Biol. Chem. (1992) [Pubmed]
  10. The 1-aminocyclopropane-1-carboxylate synthase of Cucurbita. Purification, properties, expression in Escherichia coli, and primary structure determination by DNA sequence analysis. Sato, T., Oeller, P.W., Theologis, A. J. Biol. Chem. (1991) [Pubmed]
  11. Cytotoxicity of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine in isolated rat kidney cells. Lash, L.H., Anders, M.W. J. Biol. Chem. (1986) [Pubmed]
  12. The chemical labeling of glutamate decarboxylase in vivo. Rando, R.R. J. Biol. Chem. (1981) [Pubmed]
  13. Alanine and glutamine synthesis and release from skeletal muscle. I. Glycolysis and amino acid release. Garber, A.J., Karl, I.E., Kipnis, D.M. J. Biol. Chem. (1976) [Pubmed]
  14. Effect of GABAergic drugs in the behavioral 'despair' test in rats. Borsini, F., Evangelista, S., Meli, A. Eur. J. Pharmacol. (1986) [Pubmed]
  15. The effects of haloalkene cysteine conjugates on cytosolic free calcium levels in LLC-PK(1) cells--studies utilising digital imaging fluorescence microscopy. Blackmore, M., Whitwell, C., Morton, J.K., Gray, T.J., Lock, E.A. Toxicology (2002) [Pubmed]
  16. Cellular effects of reactive intermediates: nephrotoxicity of S-conjugates of amino acids. Anders, M.W., Elfarra, A.A., Lash, L.H. Arch. Toxicol. (1987) [Pubmed]
  17. Neurodegenerative disorders: clues from glutamate and energy metabolism. Ikonomidou, C., Turski, L. Critical reviews in neurobiology. (1996) [Pubmed]
  18. Non-invasive neurochemical analysis of focal excitotoxic lesions in models of neurodegenerative illness using spectroscopic imaging. Jenkins, B.G., Brouillet, E., Chen, Y.C., Storey, E., Schulz, J.B., Kirschner, P., Beal, M.F., Rosen, B.R. J. Cereb. Blood Flow Metab. (1996) [Pubmed]
  19. Age-dependent neurotoxicity of striatal lesions produced by aminooxyacetic acid: quantitative in vitro 1H NMR spectroscopic studies. Chang, C., Jang, T. J. Neurochem. (1995) [Pubmed]
  20. Proenkephalin gene regulation in the paraventricular nucleus by GABA: interactions with opioid systems in a transgenic model. Borsook, D., Falkowski, O., Smirnova, O. J. Neurochem. (1998) [Pubmed]
  21. Glutamate transport and metabolism in astrocytes. Sonnewald, U., Westergaard, N., Schousboe, A. Glia (1997) [Pubmed]
  22. Hydrogen sulfide inhibits nitric oxide production and nuclear factor-kappaB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide. Oh, G.S., Pae, H.O., Lee, B.S., Kim, B.N., Kim, J.M., Kim, H.R., Jeon, S.B., Jeon, W.K., Chae, H.J., Chung, H.T. Free Radic. Biol. Med. (2006) [Pubmed]
  23. Rat brain slices produce and liberate kynurenic acid upon exposure to L-kynurenine. Turski, W.A., Gramsbergen, J.B., Traitler, H., Schwarcz, R. J. Neurochem. (1989) [Pubmed]
  24. Changes in the amino acid content of nerve endings (synaptosomes) induced by drugs that alter the metabolism of glutamate and gamma-aminobutyric acid. Geddes, J.W., Wood, J.D. J. Neurochem. (1984) [Pubmed]
  25. Aspartate aminotransferase for synthesis of transmitter glutamate in the medulla oblongata: effect of aminooxyacetic acid and 2-oxoglutarate. Kihara, M., Kubo, T. J. Neurochem. (1989) [Pubmed]
  26. Biliary excretion of glutathione conjugates of 4,5-epoxy-4,5-dihydro-1- nitropyrene and 9,10-epoxy-9,10-dihydro-1-nitropyrene in rats administered 1-nitropyrene orally and their further metabolism in the intestinal tract. Kinouchi, T., Nishifuji, K., Ohnishi, Y. Carcinogenesis (1990) [Pubmed]
  27. Some characteristics of glutamic acid decarboxylase of chick ampullary cristae. Meza, G. J. Neurochem. (1984) [Pubmed]
  28. Concomitant increases in serum growth hormone and hypothalamic somatostatin in rats after injection of gamma-aminobutyric acid, aminooxyacetic acid, or gamma-hydroxybutyric acid. Takahara, J., Yunoki, S., Hosogi, H., Yakushiji, W., Kageyama, J., Ofuji, T. Endocrinology (1980) [Pubmed]
  29. Uptake of nephrotoxic S-conjugates by isolated rat renal proximal tubular cells. Lash, L.H., Anders, M.W. J. Pharmacol. Exp. Ther. (1989) [Pubmed]
  30. GABAergic regulation of enkephalin in rat striatum: alterations in Met5-enkephalin level, precursor content and preproenkephalin messenger RNA abundance. Sivam, S.P., Hong, J.S. J. Pharmacol. Exp. Ther. (1986) [Pubmed]
  31. Nephrotoxicity of the glutathione and cysteine conjugates of 2-bromo-2-chloro-1,1-difluoroethene. Finkelstein, M.B., Baggs, R.B., Anders, M.W. J. Pharmacol. Exp. Ther. (1992) [Pubmed]
  32. Spasmodic, a mutation on chromosome 11 in the mouse. Lane, P.W., Ganser, A.L., Kerner, A.L., White, W.F. J. Hered. (1987) [Pubmed]
  33. Inhibitors of crayfish glutamic acid decarboxylase. Grossfeld, R.M., Yancey, S.W., Baxter, C.F. Neurochem. Res. (1984) [Pubmed]
  34. Failure of aminooxyacetic acid therapy in Huntington disease. Perry, T.L., Wright, J.M., Hansen, S., Allan, B.M., Baird, P.A., MacLeod, P.M. Neurology (1980) [Pubmed]
  35. Changes in the effect of gamma-aminobutyric acid on prolactin secretion during sexual maturation in female rats. Moguilevsky, J.A., Carbone, S., Szwarcfarb, B. Endocrinology (1992) [Pubmed]
  36. Regional variation in gamma-aminobutyric acid turnover: effect of castration on gamma-aminobutyric acid turnover in microdissected brain regions of the male rat. Grattan, D.R., Selmanoff, M. J. Neurochem. (1993) [Pubmed]
  37. Focal microinjection of gamma-acetylenic GABA into the rat entorhinal cortex: behavioral and electroencephalographic abnormalities and preferential neuron loss in layer III. Wu, H.Q., Schwarcz, R. Exp. Neurol. (1998) [Pubmed]
  38. Neuronal damage after the injection of aminooxyacetic acid into the rat entorhinal cortex: a silver impregnation study. Du, F., Eid, T., Schwarcz, R. Neuroscience (1998) [Pubmed]
  39. Effect of aminooxyacetic acid on extracellular level of D-serine in rat striatum: an in vivo microdialysis study. Hashimoto, A., Yoshikawa, M. Eur. J. Pharmacol. (2005) [Pubmed]
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