Gene Review:
Gpt - glutamic-pyruvate transaminase (alanine...
Rattus norvegicus
Synonyms:
ALT1, Aat1, Alanine aminotransferase 1, GPT 1, Glutamate pyruvate transaminase 1, ...
Vos,
Gouw,
Klok,
Havinga,
van Goor,
Huitema,
Roelofsen,
Kuipers,
Jansen,
Moshage,
Bilodeau,
Aubry,
Houle,
Burnes,
Ethier,
He,
Luo,
Wang,
Wang,
Fu,
Xu,
Zhao,
Liu,
Suliburk,
Helmer,
Gonzalez,
Robinson,
Mercer,
Muntané,
Rodríguez,
Segado,
Quintero,
Lozano,
Siendones,
Pedraza,
Delgado,
O'Valle,
García,
Montero,
De La Mata,
Miño,
- Clinical value of the determination of serum guanase activity. Studies on patients and experimental data from mongrel dogs and cultured rat hepatocytes. Ito, S., Takaoka, T., Nakaya, Y., Hiasa, Y., Mori, H., Tanaka, K., Ichihara, A. Gastroenterology (1982)
- Arterial lesions in repeatedly bred spontaneously hypertensive rats. Wexler, B.C., Iams, S.G., Judd, J.T. Circ. Res. (1976)
- Aminotransferase activities and involution of the thymus in rats bearing AH 130 tumors. Isohashi, F., Tsukanaka, K., Terada, M., Nakanishi, Y., Tani, S., Sakamoto, Y. Cancer Res. (1980)
- Contribution of no-reflow phenomenon to hepatic injury after ischemia-reperfusion: evidence for a role for superoxide anion. Koo, A., Komatsu, H., Tao, G., Inoue, M., Guth, P.H., Kaplowitz, N. Hepatology (1992)
- Modification of galactosamine-induced liver injury in rats by reticuloendothelial system stimulation or depression. Al-Tuwaijri, A., Akdamar, K., Di Luzio, N.R. Hepatology (1981)
- The hepatoprotective and therapeutic effects of propolis ethanol extract on chronic alcohol-induced liver injuries. Lin, S.C., Lin, Y.H., Chen, C.F., Chung, C.Y., Hsu, S.H. Am. J. Chin. Med. (1997)
- Dedifferentiated variants of a rat hepatoma: partial reversion induced by cell aggregation. Deschatrette, J. Cell (1980)
- Enzymatic adaptation to physical training under beta-blockade in the rat. Evidence of a beta 2-adrenergic mechanism in skeletal muscle. Ji, L.L., Lennon, D.L., Kochan, R.G., Nagle, F.J., Lardy, H.A. J. Clin. Invest. (1986)
- Binge ethanol exposure increases liver injury in obese rats. Carmiel-Haggai, M., Cederbaum, A.I., Nieto, N. Gastroenterology (2003)
- Vitamin E reduces oxidant injury to mitochondria and the hepatotoxicity of taurochenodeoxycholic acid in the rat. Sokol, R.J., McKim, J.M., Goff, M.C., Ruyle, S.Z., Devereaux, M.W., Han, D., Packer, L., Everson, G. Gastroenterology (1998)
- Differential effects of nitric oxide synthase inhibitors on endotoxin-induced liver damage in rats. Vos, T.A., Gouw, A.S., Klok, P.A., Havinga, R., van Goor, H., Huitema, S., Roelofsen, H., Kuipers, F., Jansen, P.L., Moshage, H. Gastroenterology (1997)
- Diverse cardiovascular responses to aortic constriction in normotensive Sprague-Dawley versus spontaneously hypertensive rats. Wexler, B.C. Am. J. Pathol. (1979)
- Lipo-PGE1, prostaglandin E1 incorporated in lipid microspheres, protects injury of the liver caused by warm ischemia reperfusion. Egashira, T., Kim, Y.I., Takayama, F., Kudo, Y., Yamanaka, Y. Free Radic. Biol. Med. (1996)
- Protective effect of melatonin against oxidative stress induced by ligature of extra-hepatic biliary duct in rats: comparison with the effect of S-adenosyl-L-methionine. López, P.M., Fiñana, I.T., De Agueda, M.C., Sánchez, E.C., Muñoz, M.C., Alvarez, J.P., De La Torre Lozano, E.J. J. Pineal Res. (2000)
- Obstructive jaundice impairs hepatic sinusoidal endothelial cell function and renders liver susceptible to hepatic ischemia/reperfusion. Yoshidome, H., Miyazaki, M., Shimizu, H., Ito, H., Nakagawa, K., Ambiru, S., Nakajima, N., Edwards, M.J., Lentsch, A.B. J. Hepatol. (2000)
- Herbal medicine Sho-saiko-to (TJ-9) prevents liver fibrosis and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet. Sakaida, I., Matsumura, Y., Akiyama, S., Hayashi, K., Ishige, A., Okita, K. J. Hepatol. (1998)
- Complete amino acid sequence of rat liver cytosolic alanine aminotransferase. Ishiguro, M., Suzuki, M., Takio, K., Matsuzawa, T., Titani, K. Biochemistry (1991)
- Hepatocyte membrane stabilization by prostaglandins E1 and E2: favorable effects on rat liver injury. Masaki, N., Ohta, Y., Shirataki, H., Ogata, I., Hayashi, S., Yamada, S., Hirata, K., Nagoshi, S., Mochida, S., Tomiya, T. Gastroenterology (1992)
- Lead and liver cell proliferation. Effect of repeated administrations. Ledda-Columbano, G.M., Columbano, A., Pani, P. Am. J. Pathol. (1983)
- TNF-alpha dependent production of inducible nitric oxide is involved in PGE(1) protection against acute liver injury. Muntané, J., Rodríguez, F.J., Segado, O., Quintero, A., Lozano, J.M., Siendones, E., Pedraza, C.A., Delgado, M., O'Valle, F., García, R., Montero, J.L., De La Mata, M., Miño, G. Gut (2000)
- Control of alanine metabolism in rat liver by transport processes or cellular metabolism. Fafournoux, P., Rémésy, C., Demigné, C. Biochem. J. (1983)
- Sinusoidal endothelial cell damage by activated macrophages in rat liver necrosis. Arai, M., Mochida, S., Ohno, A., Ogata, I., Fujiwara, K. Gastroenterology (1993)
- Decreased toxicity of polymorphonuclear neutrophils toward hepatocytes isolated from rats with acute inflammatory reaction. Mavier, P., Rosenbaum, J., Preaux, A.M., Mallat, A., Dhumeaux, D. Hepatology (1990)
- Induction of cellular resistance against Kupffer cell-derived oxidant stress: a novel concept of hepatoprotection by ischemic preconditioning. Schauer, R.J., Gerbes, A.L., Vonier, D., op den Winkel, M., Fraunberger, P., Bilzer, M. Hepatology (2003)
- Effects of extract from Ginkgo biloba on carbon tetrachloride-induced liver injury in rats. He, S.X., Luo, J.Y., Wang, Y.P., Wang, Y.L., Fu, H., Xu, J.L., Zhao, G., Liu, E.Q. World J. Gastroenterol. (2006)
- Pathophysiological differences between paired and communal breeding of male and female Sprague-Dawley rats. Wexler, B.C., Greenberg, B.P. Circ. Res. (1978)
- Inhibition of 5-lipoxygenase promotes the regeneration of the liver after partial hepatectomy in normal and icteric rats. Urade, M., Izumi, R., Kitagawa, H. Hepatology (1996)
- Stimulated hepatic tissue repair underlies heteroprotection by thioacetamide against acetaminophen-induced lethality. Chanda, S., Mangipudy, R.S., Warbritton, A., Bucci, T.J., Mehendale, H.M. Hepatology (1995)
- Effect of central urocortin on carbon tetrachloride-induced acute liver injury in rats. Yokohama, S., Yoneda, M., Watanobe, H., Kono, T., Nakamura, K., Makino, I., Terano, A. Neurosci. Lett. (2001)
- Ketamine attenuates liver injury attributed to endotoxemia: role of cyclooxygenase-2. Suliburk, J.W., Helmer, K.S., Gonzalez, E.A., Robinson, E.K., Mercer, D.W. Surgery (2005)
- Mechanism of salutary effects of androstenediol on hepatic function after trauma-hemorrhage: role of endothelial and inducible nitric oxide synthase. Shimizu, T., Szalay, L., Choudhry, M.A., Schwacha, M.G., Rue, L.W., Bland, K.I., Chaudry, I.H. Am. J. Physiol. Gastrointest. Liver Physiol. (2005)
- Insights into the role of interleukin-6 in the induction of hepatic injury after trauma-hemorrhagic shock. Toth, B., Yokoyama, Y., Schwacha, M.G., George, R.L., Rue, L.W., Bland, K.I., Chaudry, I.H. J. Appl. Physiol. (2004)
- Effects of a p38 mitogen-activated protein kinase inhibitor as an additive to university of wisconsin solution on reperfusion injury in liver transplantation. Yoshinari, D., Takeyoshi, I., Kobayashi, M., Koyama, T., Iijima, K., Ohwada, S., Matsumoto, K., Morishita, Y. Transplantation (2001)
- Increased biliary secretion and loss of hepatic glutathione in rat liver after nifurtimox treatment. Dubin, M., Moreno, S.N., Martino, E.E., Docampo, R., Stoppani, A.O. Biochem. Pharmacol. (1983)
- Androstenediol administration after trauma-hemorrhage attenuates inflammatory response, reduces organ damage, and improves survival following sepsis. Szalay, L., Shimizu, T., Suzuki, T., Hsieh, Y.C., Choudhry, M.A., Schwacha, M.G., Bland, K.I., Chaudry, I.H. Am. J. Physiol. Gastrointest. Liver Physiol. (2006)
- Free radical-dependent dysfunction of small-for-size rat liver grafts: prevention by plant polyphenols. Zhong, Z., Connor, H.D., Froh, M., Bunzendahl, H., Lind, H., Lehnert, M., Mason, R.P., Thurman, R.G., Lemasters, J.J. Gastroenterology (2005)
- Activated neutrophils injure the isolated, perfused rat liver by an oxygen radical-dependent mechanism. Dahm, L.J., Schultze, A.E., Roth, R.A. Am. J. Pathol. (1991)
- Tezosentan, an endothelin receptor antagonist, limits liver injury in endotoxin challenged cirrhotic rats. Urbanowicz, W., Sogni, P., Moreau, R., Tazi, K.A., Barriere, E., Poirel, O., Martin, A., Guimont, M.C., Cazals-Hatem, D., Lebrec, D. Gut (2004)
- Polyphenols from Camellia sinenesis prevent primary graft failure after transplantation of ethanol-induced fatty livers from rats. Zhong, Z., Connor, H.D., Froh, M., Lind, H., Bunzendahl, H., Mason, R.P., Thurman, R.G., Lemasters, J.J. Free Radic. Biol. Med. (2004)
- Evaluation of hepatocyte injury following partial ligation of the left portal vein. Bilodeau, M., Aubry, M.C., Houle, R., Burnes, P.N., Ethier, C. J. Hepatol. (1999)